Publications

1. Ciortan L, Gan AM, Cecoltan S, Serbanescu M, Mihaila AC, Macarie RD, Tucureanu MM, Naie ML, Preda MB, Cosman BP, Bila G, Bilyy R, Butoi E. Factors Released by Polarized Neutrophil-like Cells Modulate Cardiac Fibroblast Phenotype and Limit the Inflammatory Response After Myocardial Infarction. Biomedicines. 2025 Nov 20;13(11):2829. IF: 3.9

2. Ciortan L, Macarie RD, Barbu E, Naie ML, Mihaila AC, Serbanescu M, Butoi E. Cross-Talk Between Neutrophils and Macrophages Post-Myocardial Infarction: From Inflammatory Drivers to Therapeutic Targets. Int J Mol Sci. 2025 Oct 30;26(21):10575. IF: 4.9

3. Cherry L, Popescu S, Neculachi CA, Nastase-Rusu EG, Marinescu-Colan CI, Cosman BP, Ciortan L, Martelli F, Simionescu M, Butoi E, Burlacu A, Preda MB. Mesenchymal stromal cells modulate neutrophil phenotype via paracrine signals. Stem Cell Res Ther. 2025 Oct 21;16(1):574. IF: 7.3

4. Mavileti SK, Bila G, Utka V, Bilyy R Jr, Bila E, Butoi E, Gupta S, Balyan P, Kato T, Bilyy R, Pandey SS.Squaraine-Peptide Conjugates as Efficient Reporters of Neutrophil Extracellular Traps-Mediated Chronic Inflammation. ACS Appl Mater Interfaces. 2025 Feb 12;17(6):9140-9154. IF: 8.2

5. Kardassis D, Vindis C, Stancu CS, Toma L, Gafencu AV, Georgescu A, Alexandru-Moise N, Molica F, Kwak BR, Burlacu A, Hall IF, Butoi E, Magni P, Wu J, Novella S, Gamon LF, Davies MJ, Caporali A, de la Cuesta F, Mitić T. Unravelling molecular mechanisms in atherosclerosis using cellular models and omics technologies. Vascul Pharmacol. 2025 Mar;158:107452. IF: 3.5

6. Iacobescu L, Ciobanu AO, Macarie R, Vadana M, Ciortan L, Tucureanu MM, Butoi E, Simionescu M, Vinereanu D.Diagnostic and Prognostic Role of Circulating microRNAs in Patients with Coronary Artery Disease-Impact on Left Ventricle and Arterial Function. Curr Issues Mol Biol. 2024 Aug 3;46(8):8499-8511. IF: 3.0

7. Barbu E, Mihaila AC, Gan AM, Ciortan L, Macarie RD, Tucureanu MM, Filippi A, Stoenescu AI, Petrea SV, Simionescu M, Balanescu SM, Butoi E. The Elevated Inflammatory Status of Neutrophils Is Related to In-Hospital Complications in Patients with Acute Coronary Syndrome and Has Important Prognosis Value for Diabetic Patients. Int J Mol Sci. 2024 May 8;25(10):5107. IF: 5.6

8. Mihaila AC, Ciortan L, Tucureanu MM, Simionescu M, Butoi E. Anti-Inflammatory Neutrophils Reprogram Macrophages toward a Pro-Healing Phenotype with Increased Efferocytosis Capacity. Cells. 2024 Jan 23;13(3):208. IF: 6

9. Tucureanu MM, Ciortan L, Macarie RD, Mihaila AC, Droc I, Butoi E, Manduteanu I. The Specific Molecular Changes Induced by Diabetic Conditions in Valvular Endothelial Cells and upon Their Interactions with Monocytes Contribute to Endothelial Dysfunction. Int J Mol Sci. 2024 Mar 6;25(5):3048. IF: 5.6

10. Macarie RD, Tucureanu MM, Ciortan L, Gan AM, Butoi E*, Mânduțeanu I*. Ficolin-2 amplifies inflammation in macrophage-smooth muscle cell cross-talk and increases monocyte transmigration by mechanisms involving IL-1β and IL-6. Sci Rep. 2023 Nov 8;13(1):19431. IF: 4.6.

11. Nicu R, Ciolacu DE, Petrovici AR, Rusu D, Avadanei M, Mihaila AC, Butoi E, Ciolacu F. 3D Matrices for Enhanced Encapsulation and Controlled Release of Anti-Inflammatory Bioactive Compounds in Wound Healing. Int J Mol Sci. 2023; 20;24(4):4213. IF: 6.208

12. Vadana M, Cecoltan S, Ciortan L, Macarie RD, Mihaila AC, Tucureanu MM, Gan AM, Simionescu M, Manduteanu I, Droc I, Butoi E. Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells. Int J Mol Sci. 2022 Mar 29;23(7):3776. IF: 6.208

13. Sanz CG, Mihaila AC, Evanghelidis A, Diculescu VC, Butoi E, Barsan MM. Quantification of cell oxygenation in 2D constructs of metallized electrospun polycaprolactone fibers encapsulating human valvular interstitial cells. Journal of Electroanalytical Chemistry. Volume 905, 15 January 2022, 116005, IF: 4.46.

14. Mihaila AC, Ciortan L, Macarie RD, Vadana M, Cecoltan S, Preda MB, Hudita A, Gan AM, Tucureanu MM, Simionescu M, Schiopu A and Butoi E. Transcriptional profiling and functional analysis of N1/N2 neutrophils reveal an immunomodulatory effect of S100A9-blockade on the pro-inflammatory N1. Front. Immunol., 2021, doi: 10.3389/fimmu.2021.708770. IF: 8.78

15. Cecoltan S, Ciortan L, Macarie RD, Vadana M, Mihaila AC, Tucureanu MM, Vlad ML, Droc I, Gherghiceanu M, Simionescu A, Simionescu DT, Butoi E and Manduteanu I. High glucose induced changes in human VEC phenotype in a 3D hydrogel derived from cell-free native aortic root. Front. Cardiovasc. Med., 2021 Aug 12;8:714573. IF: 6.05

16. Ciortan L, Macarie RD, Cecoltan S, Vadana M, Tucureanu MM, Mihaila AC, Droc I, Butoi E, Manduteanu I. Chronic High Glucose Concentration Induces Inflammatory and Remodeling Changes in Valvular Endothelial Cells and Valvular Interstitial Cells in a Gelatin Methacrylate 3D Model of the Human Aortic Valve. Polymers (Basel). 2020 Nov 25;12(12):2786. doi: 10.3390/polym12122786. IF: 4.32

17. Wu X, Niculite CM, Preda MB, Rossi A, Tebaldi T, Butoi E, White MK, Tudoran OM, Petrusca DN, Jannasch AS, Bone WP, Zong X, Fang F, Burlacu A, Paulsen MT, Hancock BA, Sandusky GE, Mitra S, Fishel ML, Buechlein A, Ivan C, Oikonomopoulos S, Gorospe M, Mosley A, Radovich M, Davé UP, Ragoussis J, Nephew KP, Mari B, McIntyre A, Konig H, Ljungman M, Cousminer DL, Macchi P, Ivan M. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS. Nat Commun. 2020 Sep 21;11(1):4755. IF: 14.92

18. Vadana M, Cecoltan S, Ciortan L, Macarie RD, Tucureanu MM, Mihaila AC, Droc I, Butoi E, Manduteanu I. Molecular mechanisms involved in high glucose-induced valve calcification in a 3D valve model with human valvular cells. J Cell Mol Med. 2020 Jun;24(11):6350-6361. IF: 5.31