Publicatii

Listă selectată de capitole de carte și articole publicate în reviste cu factor de impact JCR

2025

Niculescu L.S. andD. Kardassis. Bridging the Gap in Transcriptomics: From Animal to Human Studies in Atherosclerosis. Chapter 9 in Book: Transcriptomics in Atherosclerosis - Deciphering Molecular Signatures and Advancing Therapeutic Strategies. Edited by: Yvan Devaux and Miron Sopić, Imprint Elsevier, ISBN: 978-0-443-33064-3, Pages 173-186, 2025; Book doi: 10.1016/C2024-0-00740-0, Chapter doi: 10.1016/B978-0-443-33064-3.00012-8.

2024

Toma L., Deleanu M., Sanda G.M., Barbălată T., Niculescu L.S., Sima A.V., Stancu C.S. Bioactive Compounds Formulated in Phytosomes Administered as Complementary Therapy for Metabolic Disorders. Int J Mol Sci. 25(8):4162, 2024. doi: 10.3390/ijms25084162 (IF 4.9, Q1).

Karagianni K., Bibi A., Madé A., Acharya S., Parkkonen M., Barbălată T., Srivastava P. K., de Gonzalo-Calvo D., Emanueli C., Martelli F., Devaux Y., Dafou D., Nossent A. Y., and on behalf of EU-CardioRNA COST Action CA17129. Recommendations for detection, validation, and evaluation of RNA editing events in cardiovascular and neurological/ neurodegenerative diseases. Molecular Therapy: Nucleic Acids, vol. 35, 2024, doi: 10.1016/j.omtn.2023.102085 (IF 8.8, Q1).

2023

Sopić M., Karaduzovic-Hadziabdic K., Kardassis D., Maegdefessel L., Martelli F., Meerson A., Munjas J., Niculescu L.S., Stoll M., Magni P., Devaux Y., CardioRNA COST Action CA17129 and AtheroNET COST Action CA21153. Transcriptomic research in atherosclerosis: Unravelling plaque phenotype and overcoming methodological challenges. J. Molec. Cell.Cardiol. Plus. 6: 100048, 2023; doi: 10.1016/j.jmccpl.2023.100048.

Acharya S., Preda M.B., Papatheodorou I., Palioura D., Giardoglou P., Tsata V., Erceg S., Barbălată T., Ben-Aicha S., Martino F., Nicastro L., Lazou A., Beis D., Martelli F., Sopic M., Emanueli C., Kardassis D., Devaux Y., EU-CardioRNA COST Action CA17129. The science behind soft skills: Do’s and Don’ts for early career researchers and beyond. A review paper from the EU-CardioRNA COST Action CA17129. Open Res Europe 3: 55, 2023; doi: 10.12688/openreseurope.15746.2.

Barbălată T., Niculescu L.S., Stancu C.S., Pinet F., Sima A.V. Elevated Levels of Circulating lncRNAs LIPCAR and MALAT1 Predict an Unfavorable Outcome in Acute Coronary Syndrome Patients. Special Issue: The Role of Non-coding RNAs Involved in Cardiovascular Diseases and Cellular Communication. Int J Mol Sci. 24(15): 12076, 2023; doi: 10.3390/ijms241512076 (IF 5.6, Q1).

Toma L., Sanda G.M., Stancu C.S., Niculescu L.S., Raileanu M., Sima A.V. Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells. Special Issue: Recent Advances in Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases. Biomolecules 13(4): 626, 2023; doi: 10.3390/biom13040626 (IF 6.064, Q2).

Deleanu M., Toma L., Sanda G.M., Barbălată T., Niculescu L.S., Sima A.V., Deleanu C., Săcărescu L., Suciu A., Alexandru G., Crişan I., Popescu M., Stancu C.S. Formulation of Phytosomes with Extracts of Ginger Rhizomes and Rosehips with Improved Bioavailability, Antioxidant and Anti-Inflammatory Effects In Vivo. Special Issue: The Study of Plant Compounds in Antioxidant Activity and Anticancer Activity. Pharmaceutics. 15(4): 1066, 2023; doi: 10.3390/pharmaceutics15041066 (IF 6.525, Q1).

2022

Barbălată T., Scărlătescu A.I., Sanda G.M., Toma L., Stancu C.S., Dorobanțu M., Micheu M.M., Sima A.V., Niculescu L.S. Mitochondrial DNA Together with miR-142-3p in Plasma Can Predict Unfavorable Outcomes in Patients after Acute Myocardial Infarction. Special Issue: Molecular Research in Cardiovascular Disease 2.0. Int J Mol Sci. 23(17): 9947, 2022; doi: 10.3390/ijms23179947 (IF 6.208, Q1).

Scărlătescu A.I., Barbălată T., Sima A.V., Stancu C., Niculescu L.S., Micheu M.M. miR-146a-5p, miR-223-3p and miR-142-3p as Potential Predictors of Major Adverse Cardiac Events in Young Patients with Acute ST Elevation Myocardial Infarction-Added Value over Left Ventricular Myocardial Work Indices. Special Issue: Diagnostic Advances in Cardiovascular Prevention. Diagnostics (Basel). 12(8): 1946, 2022; doi: 10.3390/diagnostics12081946 (IF 3.992, Q2).

Sanda G.M., Toma L., Barbălată T., Moraru O.E., Niculescu L.S., Sima A.V., Stancu C.S. Clusterin, paraoxonase 1 and myeloperoxidase alterations induce HDL dysfunction and contribute to peripheral artery disease; aggravation by type 2 diabetes mellitus. Biofactors 48(2):454-468, 2022; doi: 10.1002/biof.1800 (IF 6.113, Q1)

Barbălată T., Moraru O.E., Stancu C.S., Sima A.V., Niculescu L.S. MiR-223-3p levels in the plasma and atherosclerotic plaques are increased in aged patients with carotid artery stenosis; association with HDL-related proteins. Special Issue: Regulatory non-coding RNAs in health and disease. Molec. Biol. Rep. 49(7):6779-6788, 2022; doi: 10.1007/s11033-021-06636-y (IF 2.316)

2021

Toma L., Barbălată T., Sanda G.M., Niculescu L.S., Sima A.V., Stancu C.S. CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction. Special Issue: Lipoproteins: From the Vital Role in Lipid Metabolism to Risk Factors for Atherosclerosis and Future Challenging Therapies, Biomolecules 11(12): 1769, 2021; doi: 10.3390/biom11121769 (IF 4.879, Q2)

Sanda G.M., Stancu C.S., Deleanu M., Toma L., Niculescu L.S., Sima A.V. Aggregated LDL turn human macrophages into foam cells and induce mitochondrial dysfunction without triggering oxidative or endoplasmic reticulum stress. PLoS One 16(1): e0245797, 2021; doi: 10.1371/journal.pone.0245797 (IF 2.74, Q2)

Toma L., Stancu C.S., Sima A.V. Endothelial Dysfunction in Diabetes Is Aggravated by Glycated Lipoproteins; Novel Molecular Therapies. Special Issue: Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches. Biomedicines 9, 18, 2021; doi: 10.3390/biomedicines9010018 (IF 4.717, Q1)

2020

Barbalata T., Moraru O.E., Stancu C.S., Devaux Y., Simionescu M., Sima A.V., Niculescu L.S. Increased miR-142 Levels in Plasma and Atherosclerotic Plaques from Peripheral Artery Disease Patients with Post-Surgery Cardiovascular Events. Special Issue: RNAs in Brain and Heart Diseases - EU-CardioRNA COST Action. Int J Mol Sci. 21(24): 9600, 2020; doi:10.3390/ijms21249600 (IF 4.556, Q1)

Barbalata T., Zhang L., Dulceanu M.D., Stancu C.S., Devaux Y., Sima A.V., Niculescu L.S. and EU-CardioRNA COST Action CA17129. Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters. Scientific Reports 10, 20549, 2020; doi: 10.1038/s41598-020-77539-4 (IF 3.998, Q1)

Toma L., Sanda G.M., Niculescu L.S., Deleanu M., Sima A.V., Stancu C.S. Phenolic Compounds Exerting Lipid-Regulatory, Anti-Inflammatory and Epigenetic Effects as Complementary Treatments in Cardiovascular Diseases. Special Issue: Phytochemical Omics in Medicinal Plants. Biomolecules. 10(4): E641, 2020; doi.org/10.3390/biom10040641 (IF 4.694, Q1) - selected as Editor's Choice Article - Video Abstract available mdpi.com/2218-273X/10/4/641

Toma L., Sanda G.M., Raileanu M., Stancu C.S., Niculescu L.S., Sima A.V. Ninjurin-1 upregulated by TNFα receptor 1 stimulates monocyte adhesion to human TNFα-activated endothelial cells; benefic effects of amlodipine. Life Sci. 249: 117518, 2020; doi.org/10.1016/j.lfs.2020.117518 (IF 3.448, Q2)

2019

Barbalata T., Deleanu M., Carnuta M.G., Niculescu L.S., Raileanu M., Sima A.V., Stancu C.S. Hyperlipidemia Determines Dysfunctional HDL Production and Impedes Cholesterol Efflux in the Small Intestine: Alleviation by Ginger Extract. Mol Nutr Food Res. 63(19): e1900029, 2019. (IF 4.653, Q1)

2018

Carnuta M.G., Deleanu M., Barbalata T., Toma L., Raileanu M., Sima A.V., Stancu C.S. Zingiber officinale extract administration diminishes steroyl-CoA desaturase gene expression and activity in hyperlipidemic hamster liver by reducing the oxidative and endoplasmic reticulum stress. Phytomedicine 48: 62-69, 2018 (IF 3.61, Q1)

Toma L., Raileanu M., Deleanu M., Stancu C.S., Sima A.V. Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression. J. Funct. Foods 48: 654–664, 2018 (IF 3.47, Q1).

Niculescu L.S., Simionescu N., Fuior E.V., Stancu C.S., Carnuta M.G., Dulceanu M.D., Raileanu M., Dragan E., Sima A.V. Inhibition of miR-486 and miR-92a decreases liver and plasma cholesterol levels by modulating lipid-related genes in hyperlipidemic hamsters. Mol. Biol. Rep. 45(4): 497-509, 2018 (IF 1.889, Q3)

Deleanu M., Popa E.E., Popa M.E. Chemical composition and active properties evaluation of wild oregano (Origanum Vulgare) and ginger (Zingiber Officinale-Roscoe) essential oils. Revista de Chimie (Bucharest) 69(8): 1927-1933, 2018 (IF 1.412, Q4)

2017

Toma L., G.M. Sanda, L. Niculescu, M Deleanu., C. Stancu, A.V. Sima. Caffeic acid attenuates the inflammatory stress induced by glycated LDL in human endothelial cells by mechanisms involving inhibition of AGE-receptor, oxidative and endoplasmic reticulum stress”, Biofactors, 2017 (IF 3.23, Q1).

Cărnuță M.G., C..S Stancu, L. Toma, G.M. Sanda, L.S. Niculescu, M. Deleanu, A.C. Popescu, M.R Popescu., A. Vlad, D.R. Dimulescu, M. Simionescu, A.V. Sima. Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients, Scientific Rep. 7(1): 7295, 2017 (IF 4.26, Q1).

Sanda G.M., M. Deleanu, L. Toma, C.S. Stancu, M Simionescu., A.V. Sima. Oxidized LDL-exposed human macrophages display increased MMP-9 expression and secretion mediated by endoplasmic reticulum stress. J Cell Biochem. 118(4): 661-669, 2017 (IF 3.08, Q2).

2016

Simionescu N., L. S. Niculescu, G.M. Sanda, M.G. Cărnuţă, C.S. Stancu, A.C. Popescu, M.R. Popescu, A. Vlad, D.R. Dimulescu, M. Simionescu, A.V. Sima. Hyperglycemia determines increased specific microRNAs levels in sera and HDL of acute coronary syndrome patients and stimulates microRNAs production in human macrophages. PLoS One 11(8): e0161201, 2016 (IF 3.54, Q1).

2015

Niculescu L.S., N. Simionescu, G.M. Sanda, M.G. Cărnuţă, C.S. Stancu, A.C. Popescu, M.R. Popescu, A. Vlad, D.R. Dimulescu, M. Simionescu, A.V. Sima.MiR-486 and miR-92a identified in circulating HDL discriminate between stable and vulnerable coronary artery disease patients. PLoS One 10(10): e0140958, 2015 (IF 3.057, Q1).

Stancu CS, Carnuta MG, Sanda GM, Toma L, Deleanu M, Niculescu LS, Sasson S, Simionescu M, Sima A.V. Hyperlipidemia-induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian hamsters. Mol Nutr Food Res. 59(11): 2293-302, 2015 (IF 4.259, Q1).

2014

Stancu C.S., Sanda G.M., Deleanu M., Sima A.V. Probiotics determine hypolipidemic and antioxidant effects in hyperlipidemic hamsters, Mol. Nutr. Food Res., 58(3): 559-568, 2014 (IF 4.259, Q1).

Simionescu, N., Niculescu, L.S., Sanda, G.M., Margină, D., Sima, A.V., Analysis of circulating microRNAs that are specifically increased in hyperlipidemic and/or hyperglycemic sera, Molecular Biology Reports, 41(9): 5765-5773, 2014.