Research
Articles
2012
- Manea A., Simionescu M. Nox enzymes and oxidative stress in atherosclerosis. Encyclopedia of Bioscience, Special issue: “Cellular and Molecular Mechanisms of Cardiovascular Diseases: Role of Oxidative Stress”, Editor Ana Fortuno, PhD, University of Navarra, Pamplona, Spain. Publisher: Frontiers in Bioscience; New York, USA, 651-670, 2012.
- Manea A, Manea SA., Florea IC., Luca CM., Raicu M. Positive regulation of Nox5-contatining NADPH oxidase by pro-inflammatory-related mechanisms in human aortic smooth muscle cells. Free Radical Biology and Medicine, 52(9):1497-1507, 2012.
- Alexandru N, Popov D, Georgescu A. Platelet dysfunction in vascular pathologies and how can it be treated. Thromb Res. 129(2):116-26, 2012.
Manduteanu I, Simionescu M. Inflammation in atherosclerosis: a cause or a result of vascular disorders? J Cell Mol Med. Review’s Serie “Cellular Dysfunction in Inflammatory – Related Vascular Disorders”, 2012. doi: 10.1111/j.1582-4934.2012.01552.x. - Pirvulescu M, Manduteanu I, Gan AM, Stan D, Simion V, Butoi E, Calin M, Simionescu M. A novel pro-inflammatory mechanism of action of resistin in human endothelial cells: Up-regulation of SOCS3 expression through STAT3 activation. Biochem Biophys Res Commun. 422(2):321-326, 2012.
- Postea O, Vasina EM, Cauwenberghs S, Projahn D, Liehn EA, Lievens D, Theelen W, Kramp BK, Butoi ED, Soehnlein O, Heemskerk JW, Ludwig A, Weber C, Koenen RR. Contribution of platelet CX(3)CR1 to platelet-monocyte complex formation and vascular recruitment during hyperlipidemia. Arterioscler Thromb Vasc Biol. 32(5):1186-1193, 2012.
- Baron M, Boulanger CM, Staels B, Tailleux A, Simionescu M. Cell-derived microparticles in atherosclerosis: biomarkers and targets for pharmacological modulation? J Cell Mol Med. 16(7):1365-1376, 2012.
- Popov D. Endoplasmic reticulum stress and the on site function of resident PTP1B. Biochem Biophys Res Commun. 422(4):535-538, 2012.
- Georgescu A, Alexandru N, Andrei E, Titorencu I, Dragan E, Tarziu C, Ghiorghe S, Badila E, Bartos D, Popov D. Circulating microparticles and endothelial progenitor cells in atherosclerosis: pharmacological effects of irbesartan. J Thromb Haemost. 10(4):680-691, 2012.
- Titorencu I, Albu M. G., Anton F., Georgescu A., Jinga V. V. Collagen – dexamethasone and collagen -D3 scaffolds for bone tissue engineering. Molecular Crystals and Liquid Crystals, 555(1): 208-217, 2012.
- Albu M.G., Suflet D.M., Chitanu G.C., Budrugeac P., Titorencu I., Trandafir V. Biocomposites based on collagen and phosphorylated dextran for bone regeneration, J. Mater. Res., 27(7): 1086-1096, 2012.
- Albu M.G., Ferdes M., Kaya D.A., Ghica M.V., Titorencu I., Popa L., Albu L. Collagen wound dressings with anti-inflamatory activity, Molecular Crystal and Liquid Crystal, 555(1): 271-279, 2012.
- Mazare A., Dilea M., Ionita D., Titorencu I., Trusca V., Vasile E. Changing bioperformance of TiO2 amorphous nanotubes as an effect of inducing crystallinity, Bioelectrochemistry, 2012. doi:10.1016/j.bioelechem.2012.01.002.
- Ghica M.V., Albu M.G., Titorencu I., Popa L., Albu L. Collagen-doxycycline topical hydrogels: rheological, kinetic and biocompatibility studies. Farmacia, 2012 (in press).
- Trusca VG, Florea IC, Kardassis D, Gafencu AV. STAT1 Interacts with RXRα to Upregulate ApoCII Gene Expression in Macrophages. PLoS One. 2012;7(7):e40463. Epub 2012.
- Niculescu L.S., Toma L., Ianas O., Sima A.V. Gene polymorphisms of CETP and apolipoprotein E in elderly subjects with cognitive impairment. Cent. Eur. J. Biol., 7(3): 419-430, 2012.
- Sanda G.M., Rogoz D., Stancu C.S., Sima A.V.Glycated LDL increase intracellular calcium concentration in human vascular smooth muscle cells. Annals of the Romanian Society for Cell Biology, vol XVII (1): 37-44, 2012 .
- Stancu C.S., Georgescu A., Toma L., Sanda G.M., Sima A.V. Glycated low density lipoproteins alter vascular reactivity in hyperlipidemic hyperglycemic hamsters. Annals of the Romanian Society for Cell Biology, vol XVII (1): 9-15, 2012.
- Toma L., Sanda G.M., Stancu C.S., Rogoz D., Sima A.V. Combined effect of inflammatory C-reactive protein and hyperglycemia on endothelial cell dysfunction. Annals of the Romanian Society for Cell Biology, vol XVII (1): 29-36, 2012.
- Stancu C.S., Toma L., Sima A.V. Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis. Cell Tissue Res. 2012 (in press).
2011
- Alexandru N, Popov D, Dragan E, Andrei E, Georgescu A. Platelet activation in hypertension associated with hypercholesterolemia: effects of irbesartan. J Thromb Haemost.; 9(1):173-84, 2011.
- Constantinescu E, Safciuc F, Sima AV. A hyperlipidemic diet induces structural changes in cerebral blood vessels. Curr Neurovasc Res.; 8(2):131-144, 2011.
- Georgescu A, Popov D, Constantin A, Nemecz M, Alexandru N, Cochior D, Tudor A. Dysfunction of human subcutaneous fat arterioles in obesity alone or obesity associated with Type 2 diabetes. Clin Sci (Lond), 120(10):463-72, 2011.
- Georgescu A. Vascular dysfunction in diabetes: The endothelial progenitor cells as new therapeutic strategy. World J Diabetes. 2011 Jun 15; 2(6):92-97.
- Georgescu A, Alexandru N, Constantinescu A, Titorencu I, Popov D. The promise of EPC-based therapies on vascular dysfunction in diabetes. Eur J Pharmacol. 2011 Nov 1; 669(1-3):1-6.
- Alexandru N., A. Georgescu, M. Amuzescu, C. Zamfir, A. Badila, D. Popov. Platelet reactivity in chronic venous insufficiency. Clin. Lab., 57 (7-8):527-534, 2011.
- Georgescu A, Alexandru N, Nemecz M, Titorencu I, Popov D. Enoxaparin reduces adrenergic contraction of resistance arterioles in aging and in aging associated with diabetes via engagement of MAP kinase pathway. Blood Coagulation and Fibrinolysis, 22(4):310-316, 2011.
- Titorencu I, M. G. Albu, L. Popa, A. Ficai, V. Jinga, M.V. Ghica. Collagen-doxycycline matrices used in tissue engineering. Farmacia, 59, 794-802, 2011
- Butoi ED, Gan AM, Manduteanu I, Stan D, Calin M, Pirvulescu M, Koenen RR, Weber C, Simionescu M. Cross talk between smooth muscle
cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules. Biochim Biophys Acta., 1813(12):2026-2035, 2011. - Fenyo IM, Florea IC, Raicu M, Manea A. Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein E-deficient mice. Vascul Pharmacol., 54(3-6):100-6, 2011.
- Haraba R, Uyy E, Suica VI, Ivan L, Antohe F. Fluvastatin reduces the high mobility group box 1 protein expression in hyperlipidemia. Internat J Cardiol, 150(1): 105-107, 2011.
- Haraba R, Suica VI, Uyy E, Ivan L, Antohe F. Hyperlipidemia stimulates the extracellular release of the nuclear high mobility group box 1 protein. Cell Tissue Res, 346(3): 361-368, 2011.
- Haraba R, Antohe F. T cells are active participants in the progression of atherosclerotic plaques. Digest J Nanomater Biostruct. 6(4): 1529-1534, 2011.
- Cojocaru VM, Ciurtin C, Uyy E, Antohe F. Nano-LC mass spectrometry proteomic tear secretion analysis in patients with secondary Sjögren’s syndrome. Digest J Nanomater Biostruct. 6(2): 507-514, 2011.
- Ivan L, Dima SO, Antohe F. Heat shock proteins in pancreatic diseases. Rom J Biochem, 48(1): 65–74, 2011.
- Heltianu C, Robciuc A, Botez G, Musina C, Stancu C, Sima AV, Simionescu M. Modified low density lipoproteins decrease the activity and expression of lysosomal acid lipase in human endothelial and smooth muscle cells. Cell Biochem Biophys. 61(1):209-16, 2011.
- Heltianu C, Guja C. Role of nitric oxide synthase family in diabetic neuropathy, J Diab Metab. Special issue, Diabetic Neuropathy, Ed. Yuriy K. Bashmakov, OMICS PUBLISHING GROUP/ACR, 2011, DOI: http://dx.doi.org/10.4172/2155-6156.S5-002. S5-002, 2011.
- Iordache F., Iordache C., Pop A., Lupu M., Andrei E., Buzila C., Maniu H. The effects of some plant lectins and extracts on EPCs adhesion, Cent. Eur. J. Biol., 6(3): 330-341, 2011.
- Liehn EA, Tuchscheerer N, Kanzler I, Drechsler M, Fraemohs L, Schuh A, Koenen RR, Zander S, Soehnlein O, Hristov M, Grigorescu G, Urs AO, Leabu M, Bucur I, Merx MW, Zernecke A, Ehling J, Gremse F, Lammers T, Kiessling F, Bernhagen J, Schober A, Weber C. Double-Edged Role of the CXCL12/CXCR4 Axis in Experimental Myocardial Infarction. J Am Coll Cardiol., 58(23):2415-23, 2011.
- Lupu M, Khalil M, Iordache F, Andrei E, Pfannkuche K, Spitkovsky D, Baumgartner S, Rubach M, Abdelrazik H, Buzila C, Brockmeier K, Simionescu M, Hescheler J, Maniu H. Direct contact of umbilical cord blood endothelial progenitors with living cardiac tissue is a requirement for vascular tube-like structures formation. J Cell Mol Med. 15(9):1914-26, 2011.
- Lupu M, Khalil M, Andrei E, Iordache F, Pfannkuche K, Neef K, Georgescu A, Buzila C, Brockmeier K, Maniu H, Hescheler J. Integration properties of Wharton’s jelly-derived novel mesenchymal stem cells into ventricular slices of murine hearts. Cell Physiol Biochem, 28,63-76, 2011.
- Manea S.A., Robciuc A., Guja C., Heltianu C. Identification of gene variants in NOS3, ET-1 and RAS that confer risk and protection against microangiopathy in type 2 diabetic obese subjects. Biochem. Biophys. Res. Commun. 407:486-490, 2011
- Pirvulescu MM, Gan AM, Stan D, Simion V, Calin M, Butoi E, Tirgoviste CI, Manduteanu I. Curcumin and a Morus alba extract reduce pro-inflammatory effects of resistin in human endothelial cells. Phytother Res., 25(12):1737-42, 2011.
- Popov D. Novel protein tyrosine phosphatase 1B inhibitors: interaction requirements for improved intracellular efficacy in type 2 diabetes mellitus and obesity control. Biochem Biophys Res Commun. 410(3):377-81, 2011.
- Rosca A.M., A. Burlacu. The effect of 5-azacytidine: Evidence for alteration of the multipotent ability of mesenchymal stem cells. Stem Cells Dev. 20(7):1213-21, 2011.
- Stan D, Calin M, Manduteanu I, Pirvulescu M, Gan AM, Butoi ED, Simion V, Simionescu M. High glucose induces enhanced expression of resistin in human U937 monocyte-like cell line by MAPK- and NF-kB-dependent mechanisms; the modulating effect of insulin. Cell Tissue Res. 343(2):379-87, 2011.
- Toma L, Stancu CS, Sanda GM, Sima AV. Anti-oxidant and anti-inflammatory mechanisms of amlodipine action to improve endothelial cell dysfunction induced by irreversibly glycated LDL. Biochem Biophys Res Commun. 411(1):202-207, 2011.
- Trusca VG, Fuior EV, Florea IC, Kardassis D, Simionescu M, Gafencu AV. Macrophage-specific up-regulation of apolipoprotein E gene expression by STAT1 is achieved via long range genomic interactions. J Biol Chem., 286(16):13891-904, 2011.
- Niculescu L.S., Robciuc M.R., Sanda G.M., Sima A.V. Apolipoprotein A-I stimulates cholesteryl ester transfer protein and apolipoprotein E secretion from lipid-loaded macrophages; the role of NF-κB and PKA signaling pathways. Biochem Biophys Res Commun. 415, 497-502, 2011.
- Stancu C., Constantinescu E., Sima A. Ceruloplasmin and oxidized LDL colocalize in atherosclerotic lesions of hamster. Centr Eur J Biol, 6(1), 23-31, 2011.
2010
- Albu M.G., M.V. Ghica, A. Ficai, I. Titorencu, L. Popa. Influence of freeze-drying process on porosity and kinetics release of collagen-doxycycline matrices. Advanced Materials and Systems. Proc of 3rd Int Conference, pp.181-186, 2010
- Chahed S., A. S. Leroyer, M. Benzerroug, D. Gaucher, A. Georgescu, S. Picaud, J-S. Silvestre, A. Gaudric, A.Tedgui, P. Massin, C.M. Boulanger. Increased vitreous shedding of microparticles in proliferative diabetic retinopathy stimulates endothelial proliferation. Diabetes, 59: 694-701, 2010
- Constantin A., Costache G. The emerging role of adipose tissue-derived leptin in inflammatory and immune responses in obesity. An update. Proc.Rom.Acad. Ser. B. 12:3-12, 2010.
- Constantin A., G. Costache, A.V. Sima , C.S.Glavce, M.Vladica, D. Popov. Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects. Biochem. Biophys. Res. Commun. 391: 282-286, 2010
- Ivan L, F Antohe. Hyperlipidemia induces endothelial-derived foam cells in culture. Recept. Signal Transduct. Res. 30(2):106-14, 2010
- Manduteanu I, Pirvulescu M, Gan AM, Stan D, Simion V, Dragomir E, Calin M, Manea A, Simionescu M. Similar effects of resistin and high glucose on P-selectin and fractalkine expression and monocyte adhesion in human endothelial cells. Biochem. Biophys. Res. Commun. 391(3):1443-8, 2010.
- Manea A, Tanase LI, Raicu M, Simionescu M. JAK/STAT3 signaling pathway regulates Nox1 and Nox4-based NADPH oxidase in Human aortic smooth muscle cells. Arterioscler. Thromb. Vasc. Biol., 30: 105-112, 2010.
- Manea A, Tanase LI, Raicu M, Simionescu M. Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-kappaB in human aortic smooth muscle cells. Biochem Biophys Res Commun. 2010; 396(4):901-7.
- Manea A. NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology. Cell Tissue Res, 342(3):325-39, 2010.
- Manea S.A., Manea A., Heltianu C. Inhibition of the JAK/STAT signaling pathway prevents high glucose-induced increase in endothelin-1 synthesis in human endothelial cells. Cell Tiss. Res., 340(1):71-79, 2010.
- Niculescu L.S., M.Vladica, A.V.Sima. Association of APOA5 and APOC3 gene polymorphisms with plasma apolipoprotein A5 level in patients with metabolic syndrome. Biochem. Biophys. Res. Commun. 391(1):587-591, 2010
- Popov D. Endothelial cell dysfunction in hyperglycemia: Phenotypic change, intracellular signaling modification, ultrastructural alteration, and potential clinical outcomes. Intl J Diabetes Mellitus, 2: 189-195, 2010.
- Popov D. Vascular smooth muscle cells phenotypic modulation by hyperglycemia: an update on underlying mechanisms. Proc. Rom. Acad. Ser. B, 12: 83-89, 2010.
- Preda M.B., A. Burlacu A. Electrocardiography as a tool for validating myocardial ischemia-reperfusion procedures in mice. Comp Med., 60(6):443-7, 2010.
- Robciuc M.R, J.Metso, A.Sima, C.Ehnholm, M. Jauhiainen. Human apoA-I increases macrophage foam cell derived PLTP activity without affecting the PLTP mass. Lipids Health Dis. 9: 9-59, 2010
- Rosca AM, Burlacu A. Isolation of a mouse bone marrow population enriched in stem and progenitor cells by centrifugation on a Percoll gradient. Biotechnol Appl Biochem. 55(4):199-208, 2010.
- Safciuc F, Constantinescu E, Sima A. The hyperlipidemic diet induces localized amyloidoses in hamster. Proc. Rom. Acad., Series B, 2: 91–99, 2010. Sima A.V., Botez G.M., Stancu C.S., Manea A., Raicu M., Simionescu M. Effect of irreversibly glycated LDL in human vascular smooth muscle cells: Lipid loading, oxidative and inflammatory stress. J. Cell. Mol. Med., 14(12): 2790-2802, 2010.
- Titorencu I., Albu M. G., Giurginca M., Jinga V., Antoniac I., Trandafir V., Cotrut C., Miculescu F., Simionescu M. In vitro biocompatibility of human endothelial cells with collagen-doxycycline matrices. Mol. Cryst. Liq. Cryst., 523: 82[654]–96[668], 2010
- Uyy E., Antohe F., Ivan L., Haraba R., Radu D.L., Simionescu M. Upregulation of caveolin-1 expression is associated with structural modifications of endothelial cells in diabetic lung, Microvasc. Res. 79: 154-159, 2010.
- Zaharia C, Niculescu M, Despa N, Simionescu M, Jinga V, Fleseriu I. Growth factors in orthopedic surgery. J Med Life. 3(1):36-51, 2010.
- Nemecz M, Popov D, Georgescu A. Phosphorylation/dephosphorylation signaling events in the aorta of streptozotocin-injected Golden Syrian Hamsters. Ann Rom Soc Cell Biol, vol XV(1), 28-34, 2010.
- Alexandru N., D. Popov, A. Georgescu. Intraplatelet oxidative/nitrative stress: inductors, consequences, and control. Trends in Cardiovascular Medicine, 20: 232-238, 2010
- Craciunescu I., Serban M., Iancu M., Revnic C., Popescu BA., Alexandru D., Rogoz D., Ginghina C. Remodelarea ventriculara post infarct si rolul matricei extracelulare. Revista Romana de Cardiologie, XXV (3), 153 – 158, 2010.
- Craciunescu I., Serban M., Iancu M., Revnic C., Popescu BA., Alexandru D., Rogoz D., Ginghina C.. Changes in plasma levels of MMP-9, MMP-7 and their inhibitors in patients with coronary artery disease. Romanian Journal of Internal Medicine, 48(2) 141-150, 2010
- Manea A., Fenyo I.M, Florea I.C, Raicu M. Distinct roles of NADPH oxidase isoforms in high glucose-induced reactive oxygen species formation in human aortic smooth muscle cells. Annals of RSCB, vol. XV, 26-32, 2010.
- Raicu M., Manea A. Activator protein -1 regulates NOX1 and NOX4-containing NADPH oxidase transcription in human vascular smooth muscle cells. Annals of RSCB, vol. XV, 11-18, 2010. Preda M.B., Burlacu A. Animal models for in vivo ischemia studies, Annals of the RSCB, XV, 115-122, 2010.
- Rosca A.-M., Burlacu A. Characterization of mesenchymal stem cells isolated from mouse bone marrow, Annals of the RSCB, XV, 57-64, 2010.
2009
- Calin MV, Manduteanu I, Dragomir E, Dragan E, Nicolae M, Gan AM, Simionescu M. Effect of depletion of monocytes/macrophages on early aortic valve lesion in experimental hyperlipidemia. Cell and Tissue Res. 336(2): 237-248, 2009 (FI: 2,74)
- Georgescu A, Alexandru N, Popov D, Amuzescu M, Andrei E, Zamfir C, Maniu H, Badila A. Chronic venous insufficiency is associated with elevated level of circulating microparticles. J Thromb Haemost. Sep; 7(9):1566-1575, 2009.
- Heltianu C., Manea S.A., Guja C., Robciuc A., Ionescu-Tirgoviste C. Polymorphism in exon 7 of the endothelial nitric oxide synthase gene is associated with low incidence of microvascular damage in type 1 diabetic neuropathy. Central European Journal of Biology, 4: 521–527, 2009.
- Ianas O., Manda D., Heltianu C., Vladoiu S., Popa O., Rosca R., Oros S., Danciulescu R. The G894T polymorphism of endothelial nitric oxide synthase gene and the endocrine-metabolic changes in metabolic syndrome: A Romanian case-control study. Acta Endocrinol., 5: 447-458, 2009.
- Manduteanu I., Dragomir E., Calin M., Gan A.M., Stan D., Pirvulescu M., Simionescu M. Resistin up-regulates fractalkine expression in human endothelial cells; lack of additive effect with TNF-alpha. Biochem. Biophys. Res. Commun. 381: 95-101, 2009.
- Simionescu M. Cellular dysfunction in inflammatory-related vascular disorders, J. Cell. Molec. Med. 13(11-12):4291-4292.
- Sima A., Stancu C., Simionescu M. Vascular endothelium in atherosclerosis. Cell Tissue Res. 335(1):191-203, 2009
- Simionescu M., Popov D., Sima A. Endothelial transcytosis in health and disease, Cell Tissue Res., 335, 27-40, 2009.
- Toma L., Stancu C.S., Botez G.M,.Sima A.V., Simionescu M. Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose, Biochem Biophys Res Commun. 390: 877-882, 2009.
- Voinea Calin M., Manduteanu I., Dragomir E., Dragan E., Nicolae M., Gan A.M., Simionescu M. Effect of monocytes/macrophages depletion on early aortic valve lesion in experimental hyperlipidemia, Cell and Tissue Research, 336(2):237-248, 2009.
- Florea IC, Trusca VG, Fenyo IM, Gafencu AV. Expression of apoE3-HRP chimeric molecule in HEK293 cells. Ann Rom Soc Cell Biol, vol. XIV(2): 21-27, 2009.
- Popov D, Nemecz M, Dumitrescu M, Georgescu A, Böhmer FD. Long-term high glucose concentration influences Akt, ERK1/2, and PTP1B protein expression in human aortic smooth muscle cells. Biochem Biophys Res Commun, 388(1):51-55, 2009.
- Avram S., Duda-Seiman D.M., Svab I., Mancas S., Duda-Seiman C., Mihailescu D.F., Current Computer Aspirin and other non-steroidal anti-inflammatory drugs as Cyclooxygenase inhibitors: state of the art, barriers and perspectives, Aided Drug Design, 5(1), 1-12, 2009.
- Raicu M., Tanase L., Manea A.. Different effect of felodipine and amlodipine on NADPH oxidase expression and function in human smooth muscle cells. Ann. Rom. Soc. Cell Biol. vol. XV, 9-13, 2009 Niculescu L.S., Toma L., Ianăş
- O., Sima A.V., Functional polymorphisms of apoE and CETP genes in aged people from Romania; association with cognitive impairment, Proc. Rom. Acad., Series B, 10(2-3), 85-89, 2009
- Burlacu A. Ombilical cord blood: not medical vaste, but important source of stem cells. Gineco.ro 2009, 5(3) 39-42, 2009.
- Burlacu A. Stem Cells: present and perspectives. Medic.ro 2009, 54, 78-81.
- Moraru A., Svab I., Mihailescu D.F., Charmm Force Field Parametrization of bacterial lipopolysaccharides, Rev. Roum. Chim. 54(10), 799-805, 2009.
2008
- Starodub OT, E.S. Demitrack, H.K. Baumgartner, M. Montrose. Disruption of COX-1 gene slows repair of microscopic lesions in the mouse gastric epithelium. Am. J. Physiol. Cell. Physiol. 249(1); C223-32, 2008.
- Alexandru N., Constantin A., Popov D. Carbonylation of platelet proteins occurs as consequence of oxidative stress and thrombin activation, and is stimulated by ageing and type 2 diabetes. Clin. Chem. Lab. Med. 46, 528–536, 2008.
- Alexandru N., Jardin I., Popov D., Simionescu M., Garcia-Estan J., Salido G. M., Rosado J.A. Effect of homocysteine on calcium mobilisation and platelet function in type 2 diabetes mellitus. J. Cell. Mol. Med. 12(5B): 2015-2026. 2008.
- Burlacu A., Rosca A.M., Maniu H., Titorencu I., Dragan E., Jinga V., Simionescu M. Promoting effect of 5-azacytidine on the myogenic differentiation of bone marrow stromal cells. Eur. J. Cell Biol. 87: 173-184, 2008.
- Chifiriuc M.C., Lixandru M., Iordache C., Bleotu C, Larion C., Olguta D., Lazar V., Antohe F., Israil A.M. Internalization of Staphylococcus aureus and Pseudomonas aeruginosa bacterial cells by non-phagocytic, epithelial human cells. Rom Biotech Lett, 13:3651-3658, 2008.
- Dragomir E., Manduteanu I., Calin M., Gan A.M., Stan D., Koenen R.R., Weber C., Simionescu M. High glucose conditions induce up-regulation of fractalkine and MCP-1 in human smooth muscle cells. Thromb. Haemost. 100: 1155–1165, 2008.
- Georgescu A, Popov D, Dragan E, Dragomir E, Badila E. Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension. Eur J Pharmacol. 81: 110-117, 2008.
- Georgescu A., Pluteanu F., Flonta M-L., Badila E., Dorobantu M., Popov D. Nebivolol induces the hyperpolarizing effect on smooth muscle cells in the mouse renal artery by activation of the β2 – adrenoceptor, Pharmacology, 81, 110-117, 2008.
- Heltianu C., Manea S.A., Guja C., Mihai C., Ionescu-Tirgoviste C. Correlation of low molecular weight advanced glycation end products and nitric oxide metabolites with chronic complications in type 1 diabetic patients, Central Eur J Biol, 3, 243-249, 2008.
- Lupu M., Gooley T., Zellmer E., Graves S.S., Storb R. Principles of peripheral blood mononuclear cell apheresis in a preclinical canine model of hematopoietic cell transplantation. Journal of Veterinary Internal Medicine 22, 74-82, 2008.
- Manea A., Manea S.A., Gafencu A.V., Raicu M., Simionescu M. Transcriptional regulation of NADPH oxidase by AP-1 in human aortic. Arterioscler. Thromb. Vasc. Biol., 28: 878-885, 2008. Popov D., Constantinescu E. Arterial smooth muscle cells dysfunction in hyperglycaemia and hyperglycaemia associated with hyperlipidaemia, from causes to effects. Arch. Physiol. Biochem., 114, 150-160, 2008.
- Robciuc M.R., Sima A.V. Modulation of phospholipid and cholesteryl ester transfer activities by alpha-tocopherol administration in the hyperlipidemic hamster. Proc. Rom. Acad. Series B, 3, 137-143, 2008.
- Sima A., Stancu C., Niculescu L., Constantinescu E., Glodeanu A., Simionescu M. The effect of simvastatin treatment on hyperlipemic hamsters. Romanian Reports in Physics 60, 857-876, 2008.
- Stancu C, Serbancea F, Botez G, Sima A. The hypocholesterolemic effect of probiotics in the hyperlipidemic hamster. Proc. Rom. Acad. Series B, 3, 145-149, 2008
- Titorencu I., Jinga V.V., Lungu A., Trandafir V., Albu M., Rau I., Iovu H. New scaffold structure based on collagen. Fabrication and biocompatibility evaluation. Molecular Crystals and Liquid Crystals, 486, 147[1189]-156[1198], 2008.
2007
- Simionescu Maya. Implications of early structural-functional changes in the endothelium for vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 27:266-274, 2007
- Manduteanu I, Dragomir E, Voinea M, Capraru M, Simionescu M. Enoxaparin Reduces H2O2-Induced Activation of Human Endothelial Cells by a Mechanism Involving Cell Adhesion Molecules and Nuclear Transcription Factors. Pharmacology. 79(3):154-162, 2007.
- Niculescu L.S., J. Fruchart-Najib, J.-C. Fruchart, A. Sima. Apolipoprotein A-V gene polymorphisms in subjects with metabolic syndrome. Clin.Chem.Lab.Med. 45(9), 1133-9, 2007.
- Sima A., A. Iordan, C. Stancu. Apolipoprotein E polymorphism – a risk factor for the metabolic syndrome. Clin. Chem. Lab. Med. 45(9): 1149-1153, 2007.
- Georgescu A, Popov D, Dragan E, Dragomir E, Badila E. Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension. Eur. J. Pharmacol, 570,149-158, 2007.
- Alexandru N., D. Popov, A. Sbarcea, M. Amuzescu. Platelet free cytosolic calcium concentration during ageing of type 2 diabetic patients, Platelets, 18(7): 473-480, 2007
- Gafencu A. V., M. R. Robciuc, E. Fuior, V. I. Zannis, D. Kardassis, M. Simionescu. Inflammatory signaling pathways regulating ApoE gene expression in macrophages. Journal of Biological Chemistry 282(30): 21776-21785, 2007
- Titorencu I., V.V. Jinga, E. Constantinescu, A.V. Gafencu, C. Ciohodaru, I. Manolescu, C. Zaharia, M. Simionescu. Proliferation, differentiation and characterization of osteoblasts from human BM mesenchymal cells. Cytotherapy, 9(7):682-696, 2007
- Safciuc F., A. Constantin, A. Manea, M. Nicolae, D. Popov, M. Raicu, D. Alexandru, E. Constantinescu. Advanced Glycation End Products, oxidative stress and metalloproteinases are altered in the cerebral microvasculature during aging, Curr Neurovasc Res, 4(4):228-234, 2007
- Corobea M. C., D. Donescu, C. Petcu, C. Radovici, S. Serban, E. Constantinescu, M. Miculescu. Polyvinyl alcohol – Na montmorillonite nanocomposites films obtained by solution intercalation, Journal of Optoelectronics and Advanced Materials, 9(11): 3358-3360, 2007
- Manea A., Manea S.A., Gafencu A.V., Raicu M. Regulation of NADPH oxidase subunit p22 phox by NF-kB in human aortic smooth muscle cells. Arch. Physiol. Bioch. 113, 163-172, 2007.
- Titorencu I., Constantinescu E., Albu M., Trandafir V., Jinga V.V., Simionescu M. Proliferation of Human Endothelial Cells on Different Collagen Supports. Proc.Rom.Acad., Ser. B, 2, 89-94, 2007
- Toma L., Sima A. The effect of high glucose concentration on nitric oxide biodisponibility. Proc. Rom. Acad., Ser. B, 1, 11-15, 2007
2006
- Balan S.A., R. Niculescu, M. Dorobantu, C. Heltianu. Association of C8002T poly-morphism in endothelin-1 gene with myocardial infarction. Analele SNBC, 10, 345-349, 2006.
- Popov D., M. Simionescu. Cellular mechanisms and signaling pathways activated by high glucose and AGE-albumin in the aortic endothelium, Arch Physiol Biochem 112: 265-273, 2006.
- Schneider Marc, Adriana Georgescu, Rose Kientsch-Engel, Peter Stahl, Doina Popov, Monika Pischetsrieder, Detection of DNA-bound advanced Glycation End-products by immunoaffinity chromatography coupled to HPLC-Diode array detection. Molecular Nutrition & Food Research, 50, 424-429, 2006.
- Georgescu Adriana, Nicoleta Alexandru, Elena Constantinescu, Doina Popov, Effect of gap junction uncoupler heptanol on resistance arteries reactivity in experimental models of diabetes, hyperlipemia and hyperlipemia-Diabetes. Vascular Pharmacology 44, 513-518, 2006.
- Georgescu A., F. Safciuc, E. Constantinescu. The effect of aging on the vasomotor function of rat basilar artery. Proceedings of the Romanian Academy, Series B, 1, 13-17, 2006.
- Dragomir E., M.Tircol, I. Manduteanu, M. Voinea, M. Simionescu. Aspirin and PPAR-α activators inhibit MCP-1 expression induced by high glucose concentration in human endothelial cells, Vascular Pharmacol., 44: 440-449, 2006.
- Dragomir E., M. Simionescu. Monocyte Chemoattractant Protein-1 –a major contributor to the inflammatory process associated with diabetes. Archives of Physiology and Biochemistry. 112(4):239-244, 2006.
- Tircol M., D. Tirziu, M. Simionescu. Chondroitin sulfate-modified LDL induces increased cholesteryl ester synthesis and down-regulation of LDL receptors in smooth muscle cells and macrophages., Central European Journal of Biology, 1, 150 – 166, 2006.
- Simionescu M., F. Antohe. Functional ultrastructure of the vascular endothelium: changes in various pathologies. In: The Vascular Endothelium, Editors: Salvador Moncada and Annie Higgs, Handb. Exp. Pharmacol., 41-69, 2006.
- Corobea M.C., Uricanu V., Donescu D., Deladi S., Radovici C., Serban S., Constantinescu E. Variable morphologies of poly(vinyl acetate)–mont- morillonite nanocomposites obtained by emulsion polymerization in the presence of poly(vinyl pyrrolidone). E-Polymers, no. 060 (ISSN 1618-7229), 2006.
- Stancu C., G. Botez, D. Alexandru, M. Vlădică, A. Sima. Lipoproteins from diabetic and hyperlipidemic patients induce an increase in scavenger receptors CD36 and LOX-1 gene expression in human endothelial cells, Proc.Rom Acad., Series B, 8, 37- 43, 2006.
- Botez G., C. Stancu, D. Alexandru, M. Vlădică, A. Sima. Glycated LDL induce lipid loading in human smooth muscle cells, Proceedings of the Romanian Academy, Series B, vol 8, pg. 31-35, 2006.
- Catana-Negreanu C., Albu R., Glavce C., Vladica M., Sima A. Apolipoprotein E genotype in the Romanian population - association with risk factors for metabolic syndrome. Proceedings of the Romanian Academy, Series B, vol 8, pg. 25-29, 2006.
- Georgescu A., F. Safciuc, E. Constantinescu. The effect of aging on the vasomotor function of rat basilar artery. Proc. Romanian Academy, Series B, 8: 13-17, 2006. Siska I. R., E. Deak, H. Maniu, D. Nistor, C. Bunu, G. Tanasie, C. Tatu, V. Ordodi, D. Szilagy, S. Anghel, C. Tatu, V. Paunescu. Isolation and culture of human adult stem cells for their differentiation towards endothelial and smooth muscle lineage. Physiology, 16/1(49): 46, 2006.
- Burlacu A. Can 5-azacytidine convert the adult stem cells into cardiomyocytes? A brief overview. Arch Physiol Biochem. 112(4/5):260-264, 2006.
- Popov D, Simionescu M. Cellular mechanisms and signaling pathways activated by high glucose and AGE-albumin in the aortic endothelium. Arch Physiol Biochem. 112: 265-273, 2006.
- Antohe F. Endothelial cells and macrophages, partners in atherosclerotic plaque progression. Arch Physiol Biochem. 112(4):245-53, 2006.
- Cojocaru V.M., Ciurtin C., Puchianu E., Antohe F. Lacrimal proteins electrophoretic analysis-diagnostic method in secondary Sjogren syndrome, Oftalmologia. 50(4), 60-63, 2006.
2005
- Georgescu A., Pluteanu F., Flonta M.-L., E. Badila, M. Dorobantu, Popov D. The cellular mechanisms involved in the vasodilator effect of nebivolol on the renal artery. Eur.J. Pharmacol., 508, 159-166, 2005
- Antohe F., Radulescu L., Puchianu E., Kennedy M.D., Low P., Simionescu M. Increased uptake of folate conjugates by activated macrophages in experimental hyperlipemia, Cell Tissue Res., 320:277-285, 2005.
- Voinea M., Manduteanu I, Dragomir E., Capraru M., Simionescu M. Immunoliposomes Directed Toward VCAM-1 Interact Specifically with Activated Endothelial Cells-A Potential Tool for Specific Drug Delivery, Pharm Res., 22(11):1906-1917, 2005.
- Manea A., Raicu M., Simionescu M. Expression of functionally phagocyte-type NAD(P)H oxidase in rat pericytes. Role of angiotensin II and high glucose. Biology of the Cell, 97:723-734, 2005.
- Constantin A, Constantinescu E, Dumitrescu M, Calin A, Popov D. Effects of ageing on carbonil stress and antioxidant defece in RBC of obese Type 2 diabetic patients. J. Cell. Mol. Med., 9 (3): 683 – 691, 2005.
- Nicolae M., M.Tircol, D.Alexandru. Inhibitory effect of acetylsalicylic acid on matrix metalloproteinase-2 activity in human endothelial cells exposed to high glucose. J. Cell. Mol. Med., 9(4), 953-960, 2005.
- Heltianu C., Costache G., Gafencu A., Diaconu M., Bodeanu M., Cristea C., Azibi K., Poenaru L., Simionescu M. Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction., J.Cell.Mol.Med., 9, 135-142, 2005.
- S. Balan, A. Cretu, M. Fenyo, C. Heltianu. Association of G894T polymorphism of eNOS gene with type 2 diabetes mellitus in men. Ann. Nat. Soc. Cell. Biol., 9(1), 32-38, 2005
- Popov D, Georgescu A, Costache G. Perturbarea reactivitatii arterelor de rezistenta, manifestare a disfunctiei vasculare in diabet. Rev. Rom. Cardiol., 20:216-223, 2005.
- Glodeanu A. A non-linear kinetic approach for chemically interacting bio-molecules and some stability-instability problems. Rom. J. Phys., 50(1-2), 199-210, 2005.
- Glodeanu A. A semi empiric approach to compute the dissociation energy of hydrogen bound to small molecules of chemical and biological interest. Rom. J. Phys., 50, 211-216, 2005.
- Glodeanu A. A linear kinetic theory for chemically interacting bio-molecules with hyperlipemic diet and drug administered to living systems. Rom.Rep.Phys., 57, 993-10001, 2005.
- Antohe F. The Folate Receptor: A Potential Candidate for Drug Targeting to Atherosclerotic Plaques. invited commentary Intl. Atherosclerosis Society (IAS) Website, 2005
- Manea A., A.V. Gafencu, S.A. Balan, M. Raicu. Mecanisme moleculare implicate in reglarea complexului NAD(P)H oxidaza in cellule musculare netede vasculare. Rolul factorului nuclear kB. Analele SNBC, 10, 53-56, 2005.
- Raicu M., Manea A. Efectul inhibitorilor ECA si al blocantilor de canale de calciu asupra stresului oxidative Indus de conditiile pro-diabetice in pericite. Analele SNBC, X, p 49-52, 2005.
2004
- Voinea M., Georgescu A., Manea A., Dragomir E., Manduteanu I., Popov D., Simionescu M. Superoxide dismutase entrapped-liposomes restore the impaired endothelium-dependent relaxation of resistance arteries in experimental diabetes, Eur. J. Pharmacol., 484, 111-118, 2004.
- Radulescu L., Stancu C., Antohe F. Antibodies against human oxidized low-density lipoprotein (LDL) as markers for human plasma modified lipoproteins. Medical Science Monitor, 10(7), BR207-214, 2004
- Radulescu L., Antohe F., Jinga V., Ghetie V., Simionescu M. Neonatal Fc receptors discriminates and monitors the pathway of native and modified immunoglobulin G in placental endothelial cells. Human Immunology 65(6), 578-585, 2004
- Manea A., Constantinescu E., Popov D., Raicu M. Changes in oxidantative balance in rat pericytes exposed to diabetic conditions. J. Cell Mol. Med., 8, 117-126, 2004.
- Radu D.L., Georgescu A., Stavaru C., Carale A., Popov D. Double transgenic mice with Type 1 diabetes develop somatic, metabolic and vascular disorders. J. Cell. Mol. Med., 8(3), 349-358, 2004.
- Fruchart-Najib J., Bauge E., Niculescu L., Pham T., Thomas B., Rommens C., Majd Z., Brewer B.,Pennacchio L.A., Fruchart J-C. Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5. Biochem. Biophys. Res. Communic. 319, 397–404, 2004
- Makarenko I, Opitz CA, Leake MC, Neagoe C, Kulke M, Gwathmey JK, del Monte F, Kajjar RJ, Linke WA. Passive stiffness changes due to upregulation of compliant titin isoforms in human DCM hearts. Circ. Res. 95, 708-716, 2004
- Dragomir E., Manduteanu I., Voinea M., Costache G., Manea A., Simionescu M. Aspirin rectifies calcium homeostasis, decreases reactive oxygen species and increases NO production in high glucose-exposed human endothelial cells. J. Diab. Complications.18, 289-299, 2004.
- Alexandru N., Rogoz D., Popov D., Sbarcea A., Amuzescu M. Efectele inaintarii in varsta asupra homeostaziei [Ca2+]i din plachetele umane. Analele SNBC, 8, 21-26, 2004.
- Svab I., Alexandru D., Vitos G., Flonta M.L. Binding affinities for sulfonamide inhibitors with matrix metalloproteinase-2 using a linear response method. J. Cell. Mol. Med., 8(4), 551-562, 2004
- Antohe F., Lin L., Kao G.Y., Poznansky M.J., Allen T.M. Transendothelial Movement of Liposomes in vitro Mediated by Cancer Cells, Neutrophils or Histamine. Journal of Liposomes Research , vol 14 (1-2), 1-25, 2004
- Toma L., Catana-Negreanu C.I., Niculescu L., Sima A. Modulation of the gene expression for low density lipoprotei receptors induced by atorvastatin. Proc. Rom. Acad., Series B, 6(2), 125-128, 2004
- Rootsi S., Magri C., Kivisild T., Benuzzi G., Help H., Bermisheva M., Kutuev I., Barac L., Pericic M., Balanovsky O., Pshenichnov A., Dion D., Grobei M., Zhivotovsky L.A., Battaglia V., Achilli A., Al-Zahery N., Parik J., King R., Cinnioglu C., Khusnutdinova E., Rudan P., Balanovska E., Scheffrahn W., Simionescu M., Brehm A., Goncalves R., Rosa A., Moisan J.P., Chaventre A., Ferak V., Furedi S., Oefner P.J., Shen P., Beckman L., Mikerezi I., Terzic R., Primorac D., Cambon-Thomsen A., Krumina A., Torroni A., Underhill P.A., Santachiara-Benerecetti A.S., Villems R., Semino O. Phylogeography of Y-Chromosome haplogroup I reveals distinct domains of prehistoric gene flow in Europe., Am. J. Hum. Genet., 75, 128-137, 2004.
- Popov D., Constantinescu E, Shepherd P.R. High glucose-induced alterations in human aortic smooth muscle cells: phenotypic changes and signal transduction mediators, Proc. Rom. Acad. Series B, 6, 47-51, 2004.
- Constantin A., Cheta D.M., Popov D., Effects of silymarin on red blood cells osmotic fragility in obesity associated with type 2 diabetes. Proc.Rom.Acad., Series B, 6(3), 187-190, 2004.
- Balan S.A., Cretu A., Fenyo M., Heltianu C. Asocierea polimorfismului G894T al genei eNos cu diabetul zaharat de tipul 2 la barbati. Analele SNBC, 9(1), 32-38, 2004.
- Voinea M., Dragomir E., Manduteanu I. Gene transfer into endothelial cells using transferrin bound cationic liposomes. Proc.Rom.Acad., Ser.B, 3:203-206, 2004.
2003
- Radulescu L., Manduteanu I., Antohe F., Simionescu M. Detection of new antigens in activated endothelial cells by high-resolution 2-D gel technology, Electrophoresis-Tech Note 2979, Bio-Rad, 2003
- Gafencu A.V., Heltianu C., Burlacu A., Hunziker W., Simionescu M. Investigation of IgG receptors expressed on the surface of human placental endothelial cells. Placenta, 24, 664-676, 2003.
- Georgescu A., Popov D., Capraru M., Simionescu M. Enoxaparin - a low molecular weight heparin, restores the altered vascular reactivity of resistance arteries in aged and aged-diabetic hamsters. Vasc. Pharmacol. 40, 167-174, 2003.
- Georgescu A., Popov D. The contractile response of the mesenteric resistance arteries to prostaglandin F2α; effects of simultaneous hyperlipidemia-diabetes. Fundam. Clin. Pharmacol. 17, 683-689, 2003
- Popov D., Simionescu M., Shepherd P.R.. Saturated-fat diet induces moderate diabetes and severe glomerulosclerosis in hamsters, Diabetologia, 46, 1408-1418, 2003
- Burlacu A. Regulation of apoptosis by Bcl-2 family proteins. J. Cell. Mol. Med. 7, 249- 257, 2003.
- Manduteanu I., Voinea M., Antohe F., Dragomir E., Capraru M., Radulescu L., Simionescu M. Effect of enoxaparin on high-glucose induced activation of endothelial cells, Eur. J. Pharmacol., 477, 269-276, 2003.
- Popescu I., Simionescu M., Tulbure D., Sima A., Catana-Negreanu C., Niculescu L., Hancu N., Gheorghe L., Mihaila M., Ciurea S., Vidu V. Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation. Transplantation, 76(9), 1345-1350, 2003.
- Neagoe C., Makarenko I., Opitz C.A., Linke W.A. Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness. J.Muscle Res Cell Motil. 24, 175-189, 2003.
- Opitz C.A., Kulke M., Leake M.C., Neagoe C., Hinssen H., Hajjar R.J., Linke W.A. Damped elastic recoil of the titin spring in myofibrils of human myocardium. Proc. Natl. Acad. Sci. USA .100:12688-12693, 2003.
- Hunter R.J., Neagoe C., Jarvelainen H.A., Martin C.R., Lindros K.O., Linke W.A., Preedy V.R. Alcohol affects the skeletal muscle proteins, titin and nebulin in male and female rats. J Nutr. 133:1154-1157, 2003.
- Avram S., Svab I., Bologa C., Flonta M.L. Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV-1 protease inhibitors. A 3D-QSAR-CoMFA method for new antiviral drug design. J. Cell Mol. Med., 7(3), 287-296, 2003.
- Burlacu A., Dragan E., Jinga V.V., Manolescu I. Aspecte morfo-functionale ale cardiomiocitelor in cultura. Analele SNBC., 8, 89-94, 2003
- Manea A., Raicu M. Efectul inhibitorilor ECA si al blocantelor de receptor AT1 asupra modificarilor induse de stresul oxidativ in retinopatia experimentala. Analele SNBC, 8, 17-20, 2003
- Balan S.A., Dobrin A., Heltianu C., Analiza polimorfismului sintetazei oxidului nitric endotelial in nefropatia diabetica. Analele SNBC, 8, 27-32, 2003
- Tircol M, Tirziu D, Simionescu M, Efecte ale activatorilor PPARα in macrofagele incubate cu LDL modificat. Analele SNBC, vol 8, 13-16, 2003.
- Glodeanu A., Sima A. A linear kinetic approach and near equilibrium thermodynamics of serum parameters from atherosclerosis- induced animals treated with drugs. Rom. J. Physics, 48, 649-657, 2003.
- Dobrin A., Balan S. A., Nesterov M., Guja C., Burtea M., Ionescu-Tirgoviste C., Heltianu C., Simionescu M. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene in Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation. Transplantation, 76(9), 1345-1350, 2003.
- Neagoe C., Makarenko I., Opitz C.A., Linke W.A. Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness. J.Muscle Res Cell Motil. 24, 175-189, 2003.
- Opitz C.A., Kulke M., Leake M.C., Neagoe C., Hinssen H., Hajjar R.J., Linke W.A. Damped elastic recoil of the titin spring in myofibrils of human myocardium. Proc. Natl. Acad. Sci. USA .100:12688-12693, 2003.
- Hunter R.J., Neagoe C., Jarvelainen H.A., Martin C.R., Lindros K.O., Linke W.A., Preedy V.R. Alcohol affects the skeletal muscle proteins, titin and nebulin in male and female rats. J Nutr. 133:1154-1157, 2003.
- Avram S., Svab I., Bologa C., Flonta M.L. Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV-1 protease inhibitors. A 3D-QSAR-CoMFA method for new antiviral drug design. J. Cell Mol. Med., 7(3), 287-296, 2003.
- Burlacu A., Dragan E., Jinga V.V., Manolescu I. Aspecte morfo-functionale ale cardiomiocitelor in cultura. Analele SNBC., 8, 89-94, 2003
- Manea A., Raicu M. Efectul inhibitorilor ECA si al blocantelor de receptor AT1 asupra modificarilor induse de stresul oxidativ in retinopatia experimentala. Analele SNBC, 8, 17-20, 2003
- Balan S.A., Dobrin A., Heltianu C., Analiza polimorfismului sintetazei oxidului nitric endotelial in nefropatia diabetica. Analele SNBC, 8, 27-32, 2003
- Tircol M, Tirziu D, Simionescu M, Efecte ale activatorilor PPARα in macrofagele incubate cu LDL modificat. Analele SNBC, vol 8, 13-16, 2003.
- Glodeanu A., Sima A. A linear kinetic approach and near equilibrium thermodynamics of serum parameters from atherosclerosis- induced animals treated with drugs. Rom. J. Physics, 48, 649-657, 2003.
- Dobrin A., Balan S. A., Nesterov M., Guja C., Burtea M., Ionescu-Tirgoviste C., Heltianu C., Simionescu M. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene in Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation. Transplantation, 76(9), 1345-1350, 2003.
- Neagoe C., Makarenko I., Opitz C.A., Linke W.A. Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness. J.Muscle Res Cell Motil. 24, 175-189, 2003.
- Opitz C.A., Kulke M., Leake M.C., Neagoe C., Hinssen H., Hajjar R.J., Linke W.A. Damped elastic recoil of the titin spring in myofibrils of human myocardium. Proc. Natl. Acad. Sci. USA .100:12688-12693, 2003.
- Hunter R.J., Neagoe C., Jarvelainen H.A., Martin C.R., Lindros K.O., Linke W.A., Preedy V.R. Alcohol affects the skeletal muscle proteins, titin and nebulin in male and female rats. J Nutr. 133:1154-1157, 2003.
- Avram S., Svab I., Bologa C., Flonta M.L. Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV-1 protease inhibitors. A 3D-QSAR-CoMFA method for new antiviral drug design. J. Cell Mol. Med., 7(3), 287-296, 2003.
- Burlacu A., Dragan E., Jinga V.V., Manolescu I. Aspecte morfo-functionale ale cardiomiocitelor in cultura. Analele SNBC., 8, 89-94, 2003
- Manea A., Raicu M. Efectul inhibitorilor ECA si al blocantelor de receptor AT1 asupra modificarilor induse de stresul oxidativ in retinopatia experimentala. Analele SNBC, 8, 17-20, 2003
- Balan S.A., Dobrin A., Heltianu C., Analiza polimorfismului sintetazei oxidului nitric endotelial in nefropatia diabetica. Analele SNBC, 8, 27-32, 2003
- Tircol M, Tirziu D, Simionescu M, Efecte ale activatorilor PPARα in macrofagele incubate cu LDL modificat. Analele SNBC, vol 8, 13-16, 2003.
- Glodeanu A., Sima A. A linear kinetic approach and near equilibrium thermodynamics of serum parameters from atherosclerosis- induced animals treated with drugs. Rom. J. Physics, 48, 649-657, 2003.
- Dobrin A., Balan S. A., Nesterov M., Guja C., Burtea M., Ionescu-Tirgoviste C., Heltianu C., Simionescu M. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene in Homozygous familial hypercholesterolemia: specific indication for domino liver transplantation. Transplantation, 76(9), 1345-1350, 2003.
- Neagoe C., Makarenko I., Opitz C.A., Linke W.A. Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness. J.Muscle Res Cell Motil. 24, 175-189, 2003.
- Opitz C.A., Kulke M., Leake M.C., Neagoe C., Hinssen H., Hajjar R.J., Linke W.A. Damped elastic recoil of the titin spring in myofibrils of human myocardium. Proc. Natl. Acad. Sci. USA .100:12688-12693, 2003.
- Hunter R.J., Neagoe C., Jarvelainen H.A., Martin C.R., Lindros K.O., Linke W.A., Preedy V.R. Alcohol affects the skeletal muscle proteins, titin and nebulin in male and female rats. J Nutr. 133:1154-1157, 2003.
- Avram S., Svab I., Bologa C., Flonta M.L. Correlation between the predicted and the observed biological activity of the symmetric and nonsymmetric cyclic urea derivatives used as HIV-1 protease inhibitors. A 3D-QSAR-CoMFA method for new antiviral drug design. J. Cell Mol. Med., 7(3), 287-296, 2003.
- Burlacu A., Dragan E., Jinga V.V., Manolescu I. Aspecte morfo-functionale ale cardiomiocitelor in cultura. Analele SNBC., 8, 89-94, 2003
- Manea A., Raicu M. Efectul inhibitorilor ECA si al blocantelor de receptor AT1 asupra modificarilor induse de stresul oxidativ in retinopatia experimentala. Analele SNBC, 8, 17-20, 2003
- Balan S.A., Dobrin A., Heltianu C., Analiza polimorfismului sintetazei oxidului nitric endotelial in nefropatia diabetica. Analele SNBC, 8, 27-32, 2003
- Tircol M, Tirziu D, Simionescu M, Efecte ale activatorilor PPARα in macrofagele incubate cu LDL modificat. Analele SNBC, vol 8, 13-16, 2003.
- Glodeanu A., Sima A. A linear kinetic approach and near equilibrium thermodynamics of serum parameters from atherosclerosis- induced animals treated with drugs. Rom. J. Physics, 48, 649-657, 2003.
- Dobrin A., Balan S. A., Nesterov M., Guja C., Burtea M., Ionescu-Tirgoviste C., Heltianu C., Simionescu M. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene in Romanian diabetic patients. Proc. Rom.Acad., 5,115-119, 2003.
2002
- Manduteanu I., Voinea M., Capraru M., Dragomir E., Simionescu M. A novel attribute of enoxaparin: inhibition of monocyte adhesion to endothelial cells by a mechanism involving cell adhesion molecules. Pharmacology, 65(1): 32-37, 2002.
- Simionescu M., Stancu C., Costache G., Sima A. Endothelial cell response to hyperlipemia. Activation-dysfunction-injury, the protective role of simvastatin. Vascular Pharmacology. 38, 275-282, 2002.
- Popov D., Costache G., Georgescu A., Enache M. Beneficial effects of L-Arginine supplementation in experimental hyperlipemia-hyperglycemia in the hamster. Cell and Tissue Research, 308, 109-120, 2002.
Constantinescu E., Alexandru D., Alexandru V. An ex vivo model to study the monocyte-endothelial cell interaction in the prelesional stage of experimentally-induced atherogenesis in hamster. J. Submicrosc. Cytol. Pathol., 34(2), 115-124, 2002. - Heltianu C., Costache G., Azibi K., Poenaru L., Simionescu M. Endothelial nitric oxide synthase gene polymorphism in Fabry’s disease. Clinical Genetics, 61, 423-429, 2002.
- Voinea M., Dragomir E., Manduteanu I., Simionescu M. Binding and uptake of transferrin-bound liposomes targeted to transferrin receptors of endothelial cells. Vascular Pharmacology, 39, 13-20, 2002.
- Neagoe C., Kulke M., del Monte F., Gwathmey J.K., de Tombe P.P., Hajjar R.J., Linke W.A. Titin isoform switch in ischemic human heart disease. Circulation, 106, 1333-41, 2002.
- Minajeva A., Neagoe C., Kulke M., Linke W.A. Titin-based contribution to shortening velocity of rabbit skeletal myofibrils. J Physiol. 540, 177-188, 2002.
- Linke W.A., Kulke M., Li H., Fujita-Becker S., Neagoe C., Manstein D.J., Gautel M., Fernandez J.M. PEVK domain of titin: an entropic spring with actin-binding properties. J Struct Biol. 137, 194-205, 2002.
- Anderson J., Joumaa V., Stevens L., Neagoe C., Li Z., Mounier Y., Linke W.A., Goubel F. Passive stiffness changes in soleus muscles from desmin knockout mice are not due to titin modifications. Pflügers Arch. 444, 771-776, 2002.
- Azibi K., Caillaud C., Heltianu C., Dussau J., Puech JP., Poenaru L. Novel mutations and genetic markers in Fabry disease. Am. J. Human Genetics, 71, 540, 2002.
- Sima A., Stancu C. Modified lipoproteins accumulate in human coronary atheroma. J. Cell. Mol. Med. 6, 110-111, 2002.
- Sima A. Experimental atheroma formation in the coronary artery of the hyperlipemic hamster. J. Cell. Mol. Med. 6, 276-277, 2002
- Voinea M., Simionescu M. Designing of “intelligent” liposomes for efficient delivery of drugs. J. Cell. Mol. Med. 6, 465-474, 2002
- Tircol M., Tirziu D., Simionescu M. Proprietatile aterogene ale LDL modificat cu condroitin sulfat si expresia genica a PPARα in macrofagele umane. Analele SNBC. VII(1), 71 – 75, 2002.
- Manea A., Constantinescu E., Raicu M. Conditiile pro-diabetice induc dezechilibrul balantei oxidanti/antioxidanti in pericite. Analele SNBC. VII (1), 76-81, 2002.
- Gafencu A.V., Dutca M., Heltianu C. Caracterizarea proteinelor care leaga albumina in celulele endoteliale placentare umane. Analele SNBC. VII, 64-68, 2002.
2001
- Antohe F., Radulescu L., Gafencu A., Ghetie V., Simionescu M. Expression of functionally active FcRn and differentiated bidirectional transport of IgG in human placental endothelial cells. Human Immunology, 62: 93-105, 2001.
- Firan M., Bawdon R., Radu C., Ober R.J., Eaken D., Antohe F., Ghetie V., Sally Ward E. The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of γ-globulin in humans. International Immunology, 13(8): 993-1002, 2001.
- Raicu M., Florea. S. Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling. Fundamental and Clinical Pharmacology, 15, 387-392, 2001.
- Georgescu A., Popov D., Simionescu M. Mechanisms of decreased bradykinin-induced vasodilation in experimental hyperlipemia-hyperglycemia: contribution of nitric oxide and Ca2+ -activated K+ channels. Fundamental and Clinical Pharmacology, 15: 335-342, 2001.
- Burlacu A., Jinga V.V., Gafencu A.V., Simionescu M. Severity of oxidative stress generates different mechanisms of endothelial cell death. Cell and Tissue Research, 306: 409-416, 2001.
- Kulke M., Neagoe C., Kolmerer B., Minajeva A., Hinssen H., Bullard B., Linke W.A. Kettin, a major source of myofibrillar stiffness in Drosophila indirect flight muscle. J Cell Biol., 154, 1045-57, 2001.
- Kulke M., Fujita-Becker S., Rostkova E., Neagoe C., Labeit D., Manstein D.J., Gautel M., Linke W.A. Interaction between PEVK-titin and actin filaments: origin of a viscous force component in cardiac myofibrils. Circ Res., 89, 874-881, 2001.
- Sima A., Stancu C., Constantinescu E., Ologeanu L., Simionescu M. The hyperlipemic hamster – a model for testing the anti-atherogenic effect of amlodipine. J. Cell. Mol. Med., 5(2), 153-162, 2001.
- Niculescu L., Stancu C., Sima A., Toporan D., Simionescu M. The total peroxyl radical trapping potential in serum – an assay to define the stage of atherosclerosis, J. Cell. Mol. Med., 5(3), 285-294, 2001
- Simionescu M. Cellular components of the air-blood barrier. J. Cell. Mol. Med., 5(3), 320-321, 2001.
- Stancu C., Sima A. Statins: mechanisms of action and effects. J. Cell. Mol. Med., 5(4): 378-387, 2001
- Stancu C., Sima A., Toporan D., Niculescu L., Catana-Negreanu C.C., Simionescu M. Anti-atherosclerotic effects of simvastatin on atheroma cells: in vivo and in vitro studies. Proceedings of the Romanian Academy, 2, 171-174, 2001.
- Georgescu A., Popov D. Vascular reactivity of the resistance arteries to potassium in combined hyperlipemia-hyperglycemia. Proceedings Romanian Academy, 2, 111-115, 2001.
- Niculescu L., Stancu C., Vladimirescu L., Sima A. In vivo study of the antioxidant effect of vitamins E and C. Proceedings of the Romanian Academy, 3, 247-251, 2001.
- Gafencu A., Heltianu C., Burlacu A., Hunziker, W. Simionescu M. Immortalization endothelial cells. Proceedings of the Romanian Academy, 2, 117-121, 2001.
- Raicu M. Detectarea cailor de actiune ale nifedipinei in modificarea concentratiei ionilor de calciu intracelular in urma interactiei celulelor in cultura cu seruri de la donatori. Probleme Curente de Biologie Celulara si Moleculara, 6,121-126, 2001
- Sváb I., Avram S., Flonta M.L. A flexible ligand docking study of the HIV-1 protease–DMP323 complex. Romanian J. Biophysical, 11(3-4), 119-132, 2001.
- Georgescu A., Popov D., Vladimirescu L. Efectul blocarii jonctiunilor de comunicare intercelulara asupra raspunsului contractil al arterelor de rezistenta. Probleme Curente de Biologie Celulara si Moleculara, 6, 85-89, 2001
- Gafencu A., Postea O., Heltianu C., Simionescu M. Serul hiperlipidemic stimuleaza legarea si endocitoza IgG de catre celulele endoteliale aortice. Probleme Curente de Biologie Celulara si Moleculara, 6, 79-84, 2001
2000
- V.V. Jinga, Gafencu A., Antohe F., Constantinescu E., Heltianu C., Raicu M., Manolescu I., Hunziker W., Simionescu M. Establishment of a pure microvascular endothelial cell line from human placenta. Placenta, 21(4), 325-336, 2000.
- Costache G., Popov D., Georgescu A., Cenuse M., Jinga V.V., Simionescu M. The effects of simultaneous hyperlipemia-hyperglycemia on the mesenteric resistance arteries, myocardium and kidney glomeruli. J. Submicrosc. Cytol. Pathol., 32, 47-58, 2000.
- Georgescu A., Popov D. Age-dependent accumulation of advanced glycation endproducts is accelerated in combined hyperlipemia and hyperglycemia, a process attenuated by L-Arginine. J. Am. Aging Assoc. 23, 33-40, 2000.
- Constantinescu E., Alexandru D., Alexandru V., Raicu M., Simionescu M. Endothelial cell-derived foam cells fail to express adhesion molecules (ICAM-1 and VCAM-1) for monocytes. J. Submicrosc. Cytol. Pathol. 32 (2), 195-201, 2000.
- Raicu M., Florea S., Costache G., Popov D., Simionescu M. Clotrimazole inhibits smooth muscle cells proliferation and has a vasodilator effect on resistance arteries. Fundamental and Clinical Pharmacology 14: 477-485, 2000.
- Dobrian A., Lazar V., Sinescu C., Mincu D., Simionescu M. Diabetic state induces lipid loading and altered expression of lipoprotein lipase in culture monocyte-derived macrophages. Atherosclerosis, 153: 191-201, 2000.
- Raicu M., Florea S., Simionescu M. Clotrimazole inhibits the increase of intracellular free calcium induced by vasoactive agents in smooth muscle cells. Current Problems and Techniques in Cellular and Molecular Biology, 5, 89-94, 2000.
- Stancu C., Sima A., Toporan D., Niculescu L., Simionescu M. Ex vivo parameters defining the stage of the atherosclerotic disease. Current Problems and Techniques in Cellular and Molecular Biology, 5, 95-100, 2000.
- Sima A., Stancu C., Constantinescu E., Ologeanu L., Simionescu M. In vivo uptake and transcytosis of LDL in the arterial wall of the hyperlipemic hamster. Current Problems and Techniques in Cellular and Molecular Biology, 5, 101-105, 2000.
- Niculescu L., Sima A., Stancu C., Vladimirescu L., Simionescu M. Antioxidant vitamin E and C treatment in hyperlipemic hamster. Current Problems and Techniques in Cellular and Molecular Biology, 5, 106-110, 2000.
- Radulescu L., Antohe F. Monoclonal antibodies to the synthetic polypeptide PS-19. Current Problems and Techniques in Cellular and Molecular Biology, 5, 511-516, 2000.
1999
- Manduteanu I., Voinea M., Serban G., Simionescu M. High glucose induces enhanced monocyte adhesion to valvular endothelial cells via a mechanism involving ICAM-1, VCAM-1 and CD18. Endothelium, 6, 315-324, 1999.
- Voinea M. Targeting of immunoliposomes to endothelial cells. B.I.F. Future, 14, 251-252, 1999.
- Tirziu D., Jinga V.V., Serban G., Simionescu M. The effects of low density lipoproteins modified by incubation with chondroitin 6-sulfate on human aortic smooth muscle cells. Atherosclerosis, 147, 155-166, 1999.
- Niculescu L., Stancu C., Simion L., Sima A., Simionescu M. In vivo study of the antioxidant capacity of the hyperlipemic hamster serum. Current Problems and Techniques in Cellular and Molecular Biology, 4, 128-131, 1999.
- Stancu C., Niculescu L., Sima A. In vitro modified lipoproteins induce a differentiated lipid loading in cultured endothelial cells. Current Problems and Techniques in Cellular and Molecular Biology, 4, 132-135, 1999.
- Costache G., Popov D., Georgescu A., Simionescu M. Functional-structural alterations of the resistance arteries in experimental hyperlipemia or hyperglycemia. Proc. Rom. Acad. Ser.B, 1, 33-37, 1999.
- Antohe F., Poznansky M.J., Simionescu M. Low density lipoprotein binding induces asymmetric redistribution of the low density lipoprotein receptors in endothelial cells. Eur. J. Cell. Biol., 78, 407-415, 1999.
1998
- Antohe F., Popov D., Radulescu L., Simionescu N., Borchers T., Spener F., Simionescu M. Heart microvessels and aortic endothelial cells express the 15kDa heart-type fatty acid-binding proteins. Eur. J. Cell Biol., 76, 102-109, 1998.
- Borvac J., Richardson J., Medesan C., Antohe F., Radu C., Simionescu M., Ghetie V., Ward E.S. Functional expression of the MHC class I related receptor, FcRn, in endothelial cells of mice. Internat. Immunol., 10, 1289-1298, 1998.
- Cenuse M., Costache G., Popov D. Markers of oxidative stress in experimental diabetes and in diabetes associated with hyperlipemia. Current Problems and Techniques in Cellular and Molecular Biology, 3, 151-153,1998.
- Constantinescu E., Heltianu C. Evidentierea imunoelectronomicroscopica a spectrinei in eritrocite si celule endoteliale. St. Cerc. Biochim., 41, 11-21, 1998.
- Gafencu A., Stanescu M., Toderici A M., Heltianu C., Simionescu M. Protein and fatty acid composition of caveolae from apical plasmalemma of aortic endothelial cells. Cell Tissue Res., 293, 101-110, 1998.
- Georgescu A., Popov D. Influenta diabetului experimental asupra celulelor peretelui vascular. St. Cerc. Biochim., 41, 107-117, 1998.
- Georgescu A., Popov D., Costache G. Vascular reactivity of resistance arteries of hyperlipemic-hyperglycemic hamsters in the presence of vasoconstrictor agents. Current Problems and Techniques in Cellular and Molecular Biology, 3, 124-129,1998.
- Mompeo B., Popov D., Sima A., Constantinescu E., Simionescu M. Diabetes induced structural changes of venous and arterial endothelium and smooth muscle cells. J. Submicrosc. Cytol. Pathol., 30, 475-484, 1998.
- Neagoe C., Gafencu A., Heltianu C. Transfection of type I receptor for immunoglobulin G in bovine aortic endothelial cells. Current Problems in Cellular and Molecular Biology, 3, 378-383, 1998.
- Raicu M., Florea S., Simionescu M. Mechanisms of clotrimazole inhibition of smooth muscle cell proliferation induced by vasoactive agents. Current Problems and Techniques in Cellular and Molecular Biology, 3, 21-25, 1998.
- Sima A., Toporan D., Raicu M., Stancu C., Iliescu C., Ioan Al., Simionescu M. The biological effect of modified lipoprotein isolated from coronary patients. Current Problems and Techniques in Cellular and Molecular Biology, 3, 119-123,1998.
- Sorop O., Niculescu L., Sinescu C., Dobrian A., Simionescu M. The differentiated effect of antioxidants upon serum lipid peroxyl radicals in patients with type II diabetes mellitus (NIDDM) and cardiovascular diseases (CAD). Current Problems and Techniques in Cellular and Molecular Biology, 3, 146-150, 1998.
- Stancu C., Raicu M., Iliescu C., Sima A. Study of the interaction between in vitro modified lipoproteins and cells of the atheroma. Current Problems and Techniques in Cellular and Molecular Biology, 3, 130-134,1998
- Tirziu D., Tircol M., Simionescu M. Uptake of chondroitin-6-sulfate modified low density lipoproteins by human aortic smooth muscle cells, in culture. Current Problems and Techniques in Cellular and Molecular Biology, 3, 135-140, 1998.
- Voinea M., Manduteanu I. Effect of antioxidants on monocyte adhesion to valvular endothelial cells grown in high glucose concentration. Current Problems and Techniques in Cellular and Molecular Biology, 3, 141-145, 1998.
- Voinea M., Manduteanu I., Simionescu M. Liposomes uptake by vascular endothelium. Current Problems and Techniques in Cellular and Molecular Biology, 3, 26-29, 1998.
1997
- Alexandru D. Biochimia si rolul fiziopatologic al moleculelor de adeziune celulara (II). Implicarea moleculelor de adeziune celulara in patologie. St. Cerc. Biochim., 40, 29-42, 1997.
- Antohe F., Serban G., Radulescu L., Simionescu M. Transcytosis of albumin in endothelial cells is Brefeldin-A independent. Endothelium, 5, 125-136, 1997.
- Constantinescu E., Alexandru D., Raicu M., Simionescu M. Exposure to hypercholesterolemic serum modifies the expression of cytoskeletal proteins in cultured endothelia. J. Submicrosc. Cytol. Pathol., 29, 543-551, 1997.
- Costache G., Hasu M., Popov D., Georgescu A. The use of the myograph technique for the investigation of the vascular reactivity. A review. Current Problems and Techniques in Cellular and Molecular Biology, 2, 38-43, 1997.
- Georgescu A., Popov D., Hasu M. Quantitative fluorimetric analysis of advanced glycation endproducts in mesenteric arteries and lens crystallin of hyperlipemic and simultaneously hyperlipemic-hyperglycemic hamsters. Current Problems and Techniques in Cellular and Molecular Biology, 2, 65-68, 1997.
- Heltianu C., Serban G., Alexandru V., Gafencu A., Simionescu N., Simionescu M. Expression of transferrin receptors in endothelial cells transfected by electroporation. Eur. J. Cell Biol., 72, 79-89, 1997.
- Manduteanu I., Corot C., Simionescu N., Meyer D., Simionescu M. Experimental evaluation of the vascular effects and transport of an iodinated macromolecular contrast medium. Invest. Radiol., 32, 447-452, 1997.
- Popov D., Hasu M., Costache G., Stern D., Simionescu M. Capillary and aortic endothelia interact in situ with nonenzymatically glycated albumin, and develop specific interactions in early experimental diabetes. Acta Diabetol., 34, 285-293, 1997.
- Popov D., Simionescu M. Alterations of lung structure in experimental diabetes, and diabetes associated with hyperlipidaemia in hamsters. Eur. Respir. J., 10, 1850-1858, 1997.
- Raicu M., Radulescu L., Simionescu M. Clotrimazole inhibits human smooth muscle cell proliferation induced by angiotensin and Bk. Current Problems and Techniques in Cellular and Molecular Biology, 2, 158-161, 1997.
- Raicu M., Pojoga L., Simionescu N., Simionescu M. The effect of ACE inhibitors on atheroma formation is potentiated by association with a calcium channel blocker. A biochemical and ultrastructural study. J. Submicrosc. Cytol. Pathol., 29, 317-328, 1997.
- Sima A., Stancu C., Starodub O., Cristea C., Simionescu M. Immunodetection of modified lipoproteins in plasma and arterial walls of patients with coronary heart disease. Rev. Roum. Med. Int., 35, 29-38, 1997.
- Sima A., Popov D., Starodub O., Stancu C., Cristea C., Stern D., Simionescu M. Pathobiology of the heart in experimental diabetes: immunolocalization of lipoproteins, immunoglobulin G, and advanced glycation endproducts proteins in diabetic and/or hyperlipidemic hamster. Lab. Invest., 77, 3-18, 1997.
- Stancu C., Sima A. High density lipoproteins (HDL) play an antioxidant role during in vitro oxidation of low density lipoproteins (LDL). Current Problems and Techniques in Cellular and Molecular Biology, 2, 53-57, 1997.
- Radulescu L., Antohe F. Preparation of cationized albumin. Rev. Roum. Biochim., 34 (1-4), 147-153, 1997.
- Heltianu C. Actualitati in terapia genica. Mod de abordare interdisciplinar. Medicina Moderna, 4, 598-600, 1997.
1996
- Alexandru D. Biochimia si rolul fiziopatologic al moleculelor de adeziune celulara (I). St. Cerc. Biochim., 39, 17-42, 1996.
- Alexandru D., S. L. Faitar, Serban G. A method for vitamin E determination in human plasma and lipoproteins. Rev. Roum. Biochim., 33, 85-92, 1996.
- Constantinescu E. Investigarea proteinelor citoscheletului celular. Metode biochimice, biofizice si moleculare. St. Cerc. Biochim., 39, 63-68, 1996.
- Dobrian A., Lazar V., Simionescu M. Irreversibly glycated albumin induces physico-chemical alterations and increased macrophage uptake of low density lipoproteins of normal and diabetic subjects. Rev. Roum. Biochim., 33, 91-102, 1996.
- Dobrian A., Lazar V., Tirziu D., Simionescu M. Increased macrophage uptake of irreversibly glycated albumin modified-low density lipoproteins of normal and diabetic subjects is mediated by non-saturable mechanisms. Biochim. Biophys. Acta, 1317, 5-14, 1996.
- Hasu M., Cristea C., Costache G., Popov D. Interaction of glycated albumins with myocardial vasculature in early experimental diabetes. Rev. Roum. Biochim., 33, 103-109, 1996.
- Manduteanu I., Corot C., Simionescu N., Meyer D., Simionescu M. Ultrastructural investigation of the vascular transport of an iodinated macromolecular contrast medium. Acad. Radiol., 2, 353-355, 1996.
- Popov D., Sima A., Stern D., Simionescu M. The pathomorphological alterations of endocardial endothelium in experimental diabetes and diabetes associated with hyperlipidemia. Acta Diabetol., 33, 41-47, 1996.
- Raicu M., Pojoga L., Simionescu N., Simionescu M. Differential effect of two calcium channel blockers - Nifedipine and Diltiazem - in atherogenesis in hypercholesterolemic hamster. J. Submicrosc. Cytol. Pathol., 28, 265-275, 1996.
- Sima A., Faitar S.L., Hobai I., Stancu C. Evidence of modification of circulating lipoproteins in patients with acute myocardial infarction or angor pectoris. Rev. Roum. Biochim., 111-122, 1996.
- Sima A., Hobai I., Stancu C., Cinteza M., Gherasim L. Correlated biochemical modifications of plasma lipoproteins in coronary heart disease: an accelerating pathologic factor. Rom. J. Internal Med., 34, 55-64, 1996.
- Simionescu M., Popov D., Sima A., Hasu M., Costache G., Faitar S., Vulpanovici A., Stancu C., Stern D., Simionescu N. Pathobiochemistry of combined diabetes and atherosclerosis studied on a novel animal model. The hyperlipemic-hyperglicemic hamster. Am. J. Pathol., 148, 997-1014, 1996. Dobrila L., Serban G., Heltianu C. Identification of albumin-binding proteins of thymocyte plasmalemma. Biosci. Rep., 16, 425-438, 1996.
- Stanescu M., Heltianu C., Simionescu M. Different protein composition of vesicle membrane and plasmalemma proper of lung capillary endothelia. Rev. Roum. Biochim., 33, 125-134, 1996.
- Constantinescu E., Alexandru D., Raicu M., Simionescu M. Cultured endothelial cells are converted into foam cells by exposure to hypercholesterolemic serum. Current Problems and Techniques in Cellular and Molecular Biology, 1, 38-42, 1996.
- Sima A., Stancu C., Starodub O., Cristea C., Simionescu M. Immunodetection of modified lipoproteins in the plasma and the arterial walls of patients with coronary heart disease. Current Problems and Techniques in Cellular and Molecular Biology, 1, 29-32, 1996.
- Sima A., Starodub O., Cristea C., Stancu C., Simionescu M. Immunolocalization of glycosylated and oxidized lipoproteins, age proteins and immunoglobulin G in the aorta, coronary arteries and aortic valves of the diabetic and/or hyperlipidemic hamster. Current Problems and Techniques in Cellular and Molecular Biology, 1, 387-390, 1996.
1995
- Dobrian A., Simionescu M. Irreversibility glycated albumin alters the physico-chemical characteristics of low density lipoproteins of normal and diabetic subjects. Biochim. Biophys. Acta, 1270, 26-35, 1995.
- Moldovan N., Heltianu C., Simionescu N., Simionescu M. Ultrastructural evidence of differential solubility in TritonX-100 of endothelial vesicles and plasma membrane. Exp. Cell Res., 219, 309-313, 1995.
- Navarro P., Caveda L., Breviario F., Manduteanu I., Lampugnani, M.G., Dejana E. Catenin - dependent and independent functions of vascular endothelial cadherin. J. Biol. Chem., 270, 30965-30972, 1995.
- Tirziu D., Dobrian A., Tasca C., Simionescu M., Simionescu N. Intimal thickenings of human aortas contain modified reassembled lipoproteins. Atherosclerosis, 112, 101-114, 1995.
1994
- Costache G., Cristea C., Hasu M., Constantinescu E., Popov D. Alterations of extracellular matrix in endothelial cells cultured in high concentration of glucose. Rev. Roum. Biochim, 31, 221-226, 1994.
- Heltianu C., Dobrila L., Stanescu M., Antohe F., Simionescu N., Silverstein S.C., Simionescu M. A method for selective radiolabeling of lung endothelium plasmalemmal vesicles, in situ. Eur. J. Cell Biol., 64, 61-70, 1994.
- Lupu C., Rizescu N., Calb M. Altered distribution of some surface glycosaminoglycans and glycoconjugates on human platelets in diabetes mellitus. Platelets, 5, 201-208, 1994.
- Moldovan N., Lupu F., Moldovan L., Simionescu N. 4-Hydroxynonenal induces membrane perturbations and inhibition of basal prostacyclin production in endothelial cells, and migration of monocytes. Cell Biol. Int., 18, 985-992, 1994.
- Moldovan N., Moldovan L., Simionescu N. Binding of vascular anticoagulant alpha-Annexin V to the aortic intima of the hypercholesterolemic rabbit - an autoradiographic study. Blood Coagul. Fibrin, 5, 921-928, 1994.
- Raicu M. Cellular structures involved in albumin interaction with preadipocytes in various stages of adipogenesis, in vitro. J. Submicrosc. Cytol. Pathol., 26, 191-202, 1994.
- Schmidt A.M., Mora R., Cao R., Yan S.D., Brett J., Ramakrishnan R., Tsang T.C., Simionescu M., Stern D. The endothelial cell binding site for advanced glycation endproducts consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide. J. Biol. Chem., 269, 9882-9888, 1994.
- Schmidt A.M., Hasu M., Popov D., Zhang J.H., Chen J., Yan S.D., Brett J., Cao R., Kuwabara K., Costache G., Simionescu N., Simionescu M., Stern D. Receptor for advanced glycation endproduct (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating proteins. Proc. Nat. Acad. Sci. USA, 91, 8807-8811, 1994.
1993
- Antohe F., Dobrila L., Heltianu C., Simionescu N., Simionescu M. Albumin binding proteins function in the receptor-mediated binding and transcytosis of albumin across cultured endothelial cells. Eur. J. Cell Biol., 60, 268-275, 1993.
- Atanasiu R., Radu A. The interaction of cationic nanoparticles with mouse capillary endothelial cells in situ and in vivo. Int. J. Pharmaceutics., 90, 119-128, 1993.
- Costache G., Hasu M., Cristea C., Popov D. Glicarea neenzimatica a proteinelor - un mecanism biochimic in patogenia complicatiilor diabetului. St. Cerc. Biochim., 36, 29-44, 1993.
- Dobrian A., Mora R., Simionescu M., Simionescu N. In vitro formation of oxidatively-modified and reassembled human LDL: antioxidant effect of albumin. Biochim. Biophys. Acta, 1169, 12-24, 1993.
- Lupu C., Calb M., Ionescu M., Lupu F. Enhanced prothrombin and intrinsic factor X activation on blood platelets from diabetic patients. Thromb. Haemostasis, 70, 579-583, 1993.
- Lupu C., Calb M., Rizescu M., Simionescu N. Distribution of some major glycoproteins on diabetic blood platelets. J. Mol. Cell Cardiol., 25, S29, 1993.
- Lupu C., Lupu F., Calb M., Simionescu N. Exposure of anionic phospholipid-rich surface promotes procoagulant activity on hyperlipidemic blood platelets. Thromb. Haemostasis, 69, 627, 1993.
- Lupu C., Manduteanu I., Calb M., Ionescu M., Simionescu N., Simionescu M. Some major plasmalemma proteins of human diabetic platelets are involved in the enhanced platelet adhesion to cultured valvular endothelial cells. Platelets, 4, 79-84, 1993.
- Lupu F., Moldovan N., Ryan J., Stern D., Simionescu N. Intrinsic procoagulant surface induced by hypercholesterolemia on rabbit aortic endothelium. Blood Coagulation and Fibrinolysis, 4, 743-752, 1993.
- Raicu M., Vral A., Thierens H., De Ridder L. Radiation damage to endothelial cells in vitro, as judged by micronucleus assay. Mutagenesis, 8, 335-339, 1993.
- Simionescu M., Simionescu N. Pro-atherosclerotic events: Pathobiochemical changes occurring in the arterial wall before monocyte migration. FASEB J, 7, 1359-1366, 1993.
- Tasca S.I., Hoffman R.J., Stoica G. Detection of Moloney murine sarcoma virus in tissues and culture cells by the polymerase chain reaction. J. Virol. Meth., 41, 255-264, 1993.
1992
- Alexandru D., Iftode C. Purification of albumin binding proteins by successive polyacrilamide gel electrophoresis. Rev. Roum. Biochim., 29, 3-5, 1992.
- Dobrila L., Antohe F., Heltianu C., Simionescu M. Albumin binding proteins of endothelial cells identified by anti-idiotypic antibodies. Int. Immunol., 4, 789-796, 1992.
- Hasu M., Popov D., Ghinea N., Dobrila L., Antohe F., Simionescu N., Simionescu M. Specific binding of albumin to cultured aortic endothelium. Acta Histochem. Cytochem., 25, 231-237, 1992.
- Iacob M., Heltianu C. One-step method for purification of immunoglobin G from rabbit serum. Rev. Roum. Biochim., 29, 107-109, 1992.
- Iftode C., Alexandru D. Chromatographic purification of the albumin binding protein of about 31 kDa. Rev. Roum. Bioch., 29, 111-115, 1992.
- Lup C. u, Calb M., A. Tudor, Simionescu N. Localization and partial characterization of galactoside-specific lectins of the plasmalemma of platelets from normal and diabetic subjects. Platelets, 3, 323-330, 1992.
- Manduteanu I., Calb M., Lupu C., Simionescu M., Simionescu N. Increased adhesion of human diabetic platelets to cultured valvular endothelial cells. J. Submicrosc. Cytol. Pathol., 24, 539-547, 1992.
- Movileanu L., Serban G., Mihailescu D., Flonta M.L., Frangopol P.T. An investigation on the topology of chaos in a multiply regulated biochemical system. Roum. J. Biophys., 2, 77-83, 1992.
- Popov D., Hasu M., Ghinea N., Simionescu N., Simionescu M. Cardiomyocytes express albumin binding proteins. J. Mol. Cell. Cardiol., 24, 989-1002, 1992.
1991
- Antohe F., Heltianu C., Simionescu M. Albumin binding proteins of endothelial cells : immunocytochemical detection of the 18kDa peptide. Eur. J. Cell Biol., 56, 34-42, 1991.
- Raicu M., Alexandru D., Fixman A., Simionescu N. Albumin binding sites are expressed on the abluminal plasma membrane of capillary endothelium. J. Submicrosc. Cytol. Pathol., 23,1-8, 1991.
- Radu A., Moldovan N. 4-Hydroxynonenal reduces junctional communications between endothelial cells in culture. Exp. Cell Res., 196, 121-126, 1991.
- Vasile E., Antohe F. An ultrastructural study of β-very low density lipoprotein uptake and transport by valvular endothelium of hyperlipidemic rabbits. J. Submicrosc. Cytol. Pathol., 23, 279-287, 1991.
- Vasile E., Manduteanu I. Transport of LDL in “Endothelial transport of macromolecules: “Transcytosis and endocytosis”. A look from Cell Biology, Simionescu M. Simionescu N. (eds.). Cell Biology Reviews, Springer International, Berlin, vol 25, 39-41. 1991.
1990
- Manduteanu I., Vasile E., Simionescu M. Uptake of low density lipoproteins by valvular endothelial cells in culture. Rev. Roum. Biochim., 27, 235-238, 1990.
- Mora R., Simionescu M., Simionescu N. Purification and partial characterization of extracellular liposomes isolated from the hyperlipidemic rabbit aorta. J. Lipid. Res., 31, 1793-1807, 1990.
- Moroianu J., Hillebrand A., Simionescu M. Albumin binding proteins are highly expressed in actively proliferating fetal and adult tissues. Eur. J. Cell Biol., 53, 20-26, 1990.
- Sima A., Bulla A., Simionescu N. Experimental obstructive coronary atherosclerosis in the hyperlipidemic hamster. J. Submicrosc. Cytol. Pathol., 22, 1-6, 1990.
1989
- Badea M., Sima A., Jinga V.V., Hörer O. The interaction between human low density lipoproteins and bovine aortic endothelial cells. Measurements of membrane fluidity. Rev. Roum. Morphol. Embryol. Physiol., 26, 95-100, 1989.
- Ghinea N., Eskenasy M., Simionescu M., Simionescu N. Endothelial albumin binding proteins are membrane-associated components expressed on the cell surface. J. Biol. Chem., 264, 4755-4758, 1989.
- Ghinea N., Hasu M., Popov D. Selective radioiodination of the apical and luminal cell surfaces: In vitro and in situ experiments on vascular endothelial cells with Iodogen - coated Sephadex. Anal. Biochem., 179, 274-279, 1989.
- Heltianu C., Dobrila L., Antohe F., Simionescu M. Evidence for thyroxine transport by the lung and heart capillary endothelium. Microvasc. Res., 37, 188-203, 1989. Hodor P., Heltianu C. Immunocytochemical localization of glyceraldehyde-3-phosphate dehydrogenase in cultured smooth muscle cells. Microcirculation, Endothelium and Lymphatics, 5, 485-503, 1989.
- Lupu F., Constantinescu E. A new freeze-drying device for platinum replica studies of the cell surface and cytoskeleton: an example using immunogold-labeled human erythrocyte. J. Electr. Microsc. Tech, 11, 76-82, 1989.
- Mora R., Lupu F., Simionescu N. Cytochemical localization of beta-lipoproteins and their components in successive stages of hyperlipidemic atherogenesis of rabbit aorta. Atherosclerosis, 79, 183-195, 1989.
- Moroianu J., Simionescu M. Affinity isolation of albumin binding proteins using nitrocellulose bound albumin. Eur. J. Cell. Biol., 50, 447-452, 1989.
- Vasile E., Antohe F., Simionescu M., Simionescu N. Transport pathways of beta-VLDL by aortic endothelium of normal and hypercholesterolemic rabbits. Atherosclerosis, 75, 195-210, 1989.
1988
- Antohe F., Dobrila L.N., Heltianu C. Histamine receptors on mast cells. Microcirculation, Endothelium and Lymphatics, 4, 469-488, 1988.
- Eskenasy M., Tasca S.I. Culture of pericytes isolated from rat adipose tissue microvasculature and characterization of their prostanoid production. Cell Biol. Int. Rep., 12, 1055-1066, 1988.
- Galis Z., Ghitescu L., Simionescu M. Fatty acid binding to albumin increases its uptake and transcytosis by the lung capillary endothelium. Eur. J. Cell Biol., 47, 358-365, 1988.
- Ghinea N., Fixman A., Alexandru D., Popov D., Hasu M., Ghitescu L., Eskenasy M., Simionescu M., Simionescu N. Identification of albumin- binding proteins in capillary endothelial cells. J. Cell Biol., 107, 231-239, 1988.
- Ghitescu L., Galis Z., Simionescu M., Simionescu N. Differentiated uptake and transcytosis of albumin in successive vascular segments. J. Submicrosc. Cytol. Pathol., 20, 657-670, 1988.
- Liu B., Poulter L., Neacsu C., Burbach J.P.H. Isolation and identification of vasopresin and oxytocin-immunoreactive substances from bovine pineal gland. J. Biol. Chem., 263, 72-75, 1988.
- Lupu C., Calb M. Changes in platelet surface in rabbits with experimental hypercholesterolemia. Atherosclerosis, 72, 77-82, 1988.
- Lupu F., Calb M., Fixman A. Alteration of phospholipid asymmetry in the membrane of spontaneously aggregated plateletes in diabetes. Thromb. Res., 50, 605-617, 1988.
- Lupu F., Constantinescu E. Erythrocyte skeleton replicas obtained with a new freeze drying device. Inst. Phys. Conf. Ser., 93, 39-40, 1988.
- Manduteanu I., Popov D., Radu A., Simionescu M. Calf cardiac valvular endothelial cells in culture. Production of glycosaminoglycans, prostacyclin and fibronectin. J. Mol. Cell. Cardiol., 20, 103-118, 1988.
- Manduteanu I., Radu A., Simionescu M. Isolation and cultivation of rabbit endocardical cells in culture. Preliminary data. Rev. Roum. Morphol. Embryol., 34, 165-169, 1988.
- Neacsu C. Endocrine system - sanguine system relationship; antiaggregant activity of the pineal polypeptidic hormone E5 on blood platelets. Arch. Roum. Path. Exp. Microbiol., 47, 125-131, 1988.
- Alexandru D., Popov D. Izolarea si caracterizarea partiala a unui proteoglican din membrana plasmatica a ficatului de sobolan. St. Cerc. Biochim., 31, 3-7, 1988.
- Filip D.A., Popov D., Alexandru D. Proteoglicani si glicozaminoglicani secretati in mediul de cultura de catre celulele interstitiale valvulare ale iepurilor hipercolesterolemici. St. Cerc. Biochim., 31, 129-132, 1988.
- Popov D., Alexandru D., Guinea-pig antibodies to proteoglycans of the culture medium of bovine aortic endothelial cells. Rev. Roum. Bioch., 25, 151-157, 1988.
- Popov D., Alexandru D., Filip D.A. Proteoglycans and glycosaminoglycans of valvular interstitial cells. Rev. Roum. Biochim., 25, 347-353, 1988.
- Popov D., Calb M., Lupu C. Marcarea cu 35SO42 a proteoglicanilor plachetari. St. Cerc. Biochim., 31, 163-169, 1988.
- Predescu D., Simionescu N., Simionescu M., Palade G.E. Binding and transcytosis of glycoalbumin by the microvascular endothelium of the murine myocardium. Evidence that the glycoalbumin behaves as a bifunctional ligand. J. Cell Biol., 107, 1729-1738, 1988.
- Simionescu M., Ghinea N., Fixman A., M. Lasker, L. Kukes, Palade G.E. The cerebral microvasculature of the rat: structure and luminal surface properties during early development. J. Submicrosc. Cytol. Pathol., 20, 243-261, 1988.
- Tasca S., Galis Z. Ultrastructural autoradiographic localization of exogenous arachidonic acid in cultured endothelial and smooth muscle cells. Prostaglandins, Leukotrienes and Essential Fatty Acids, 33,165-171, 1988.
1987
- Alexandru D., Popov D. Sulphated proteoglycans of the endothelial cell surface of pig heart valves. Rev. Roum. Biochim., 24, 289-297, 1987.
- Clark M.R., Mel S., Lupu F., Friend D.S. Influence of the membrane undercoat on filipin perturbation of the red blood cell membrane. Exp. Cell Res., 171, 321-330, 1987.
- Filip D.A., Nistor A., Bulla A., Radu A., Simionescu M. Cellular events in the development of the valvular atherosclerotic lesions induced by experimental atherosclerosis. Atherosclerosis, 67, 199-214, 1987.
- Ghinea N., Leabu M., Hasu M., Muresan V., Colceag J., Simionescu N. Prelesional events in atherogenesis. Changes induced by hypercholesterolemia in the cell surface chemistry of arterial endothelium and blood monocytes in rabbit. J. Submicrosc. Cytol. Pathol., 19, 209-227, 1987.
- Leabu M., Ghinea N., Muresan V., Colceag J., Hasu M., Simionescu N. Cell surface chemistry of arterial endothelium and blood monocytes in the normolipidemic rabbit. J. Submicrosc. Cytol. Pathol., 19, 193-208, 1987.
- Lupu F. Criofixarea si crioprezervarea probelor biologice. St.Cerc.Bioch., 30, 77-90, 1987
- Lupu F. Dezvoltari recente ale tehnicii de inghetare fracturare. St.Cerc.Biol., Biol.Anim., 39, 125-131, 1987.
- Lupu F., Danaricu I., Simionescu N. Development of intracellular lipid deposits in the lipid laden cells of the atherosclerotic lesions. A cytochemical and ultrastructural study. Atheroscerosis, 67, 127-142, 1987.
- Lupu F., Petrescu S. Two improvements of polaron quick freezing slammer. J. Electron Microsc. Tech., 7, 235-236, 1987.
- Moldovan N., Radu A., Simionescu N. Endothelial cell plasma membrane obtained by chemically induced vesiculation. Exp. Cell. Res., 17, 499-510, 1987.
- Mora R., Lupu F., Simionescu N. Prelesional events in atherogenesis. Colocalization of apolipoprotein B, unesterified cholesterol and extracellular phospholipid liposomes in the aorta of hyperlipidemic rabbit. Atherosclerosis, 68, 143-154, 1987.
- Muresan V. Intracellular fate of a multivalent ligand covalently bound to cell surface components. An electronmicroscopic study. J. Submicrosc. Cytol. Pathol., 19, 375-385, 1987.
- Muresan V., Simionescu N. High and low molecular weight tracers for the electron microscopical detection of syaloglycoconjugates. Histochem. J., 19, 170-178, 1987.
- Nistor A., Bulla A., Filip D.A., Radu A. The hyperlipidemic hamster as a model of experimental atherosclerosis. Atherosclerosis, 68, 159-173, 1987.
- Popov D., Manduteanu I. Synthesis and secretion of 3H-mannose labeled proteins by valvular endothelial cells in culture. Rev. Roum. Biochim., 24, 49-54, 1987.
- Simionescu M., Ghitescu L., Fixman A., Simionescu N. How plasma macromolecules cross the endothelium. News Physiol. Sci., 2, 97-100, 1987.
- Simionescu N. Cell biology trends in biomedical basic research. Revue Journal, Romania, 2/1987, 112-119, 1987.
- Simionescu N. Tendinte ale biologiei celulare in cercetarea fundamentala biomedicala. Revista UNESCO, Romania, 2/1987, 103-109, 1987.
- Simionescu N. Tendence de le biologie cellulaire dans la recherche biomedicale fondamentale. Revue Journal, Romania, 2/1987, 27-34, 1987.
- Popov D., Manduteanu I. Synthesis and secretion of 3H-mannose labeled proteins by valvular endothelial cells in culture. Rev.Roum. Biochem.. 24,1, 48-54, 1987.
- Hodor P., Heltianu C. Structural and immunochemical studies on rabbit erythrocyte spectrin. Rev. Roum. Biochim., 24, 229-234, 1987.
1986
- Antohe F., Heltianu C., Simionescu M. Further evidence for the distribution and nature of histamine receptors on microvascular endothelium. Microcirculation, Endothelium and Lymphatics, 3, 163-185, 1986.
- Constantinescu E., Heltianu C., Simionescu M. Immunological detection of an analogue of the erythroid protein 4.1 in endothelial cells. Cell. Biol. Int. Rep., 10, 861-868, 1986.
- Filip D.A., Radu A., Simionescu M. Interstitial cells of heart valves possess characteristics similar to smooth muscle cells. Circ. Res., 59, 310-320, 1986.
- Georgescu L., Antohe F., Simionescu N. The permeability of aortic endothelium to 125I-BSA in hyperlipidemic hamster. Effect of histamine and serotonin, Rev. Roum. Morphol. Embryol. Physiol., 23, 231-235, 1986.
- Ghinea N. Cationic hemeundecapeptide as stain for detecting glycosaminoglycans on cellulose acetate strips. Anal. Biochem. 155, 78-82, 1986.
- Ghinea N., Hasu M. Charge effect on binding uptake and transport of ferritin through fenestrated endothelium. J. Submicrosc. Cytol., 18, 647-659, 1986.
- Ghitescu L., Fixman A., Simionescu M., Simionescu N. Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis. J. Cell Biol., 102,1304-1311, 1986.
- Heltianu C., Bogdan I., Constantinescu E., Simionescu M. Endothelial cells express a spectrin-like cytoskeletal protein. Circ. Res., 58, 605-610, 1986.
- Heltianu C., Constantinescu E., Simionescu M. Blood plateletes express proteins immunologically related to red cell spectrin and band 4. 1. Rev. Roum. Biochim., 23, 189-194, 1986.
- Jinga V.V., Badea M.G., Hörer O. Evidence that some membrane ligands modulate the plasmalemma fluidity of endothelial cells in culture Rev. Roum. Morphol. Embryol. Physiol.: Physiologie, 23, 91-98, 1986.
- Jinga V.V., Bogdan I., Fruchter J. Experimental model for the quantitative estimation of transendothelial transport in vitro; a two-compartment system. Rev. Roum. Morphol., Embryol. Physiol.: Physiologie, 23, 227-236, 1986.
- Lupu F. Tehnica de inghetare - fracturare: principii, metodologie, aplicatii si interpretare. St. Cerc. Biol., Seria Biol. Anim., 38, 115-123, 1986.
- Lupu F., Calb M., Scurei C., Simionescu N. Changes in the organization of membrane lipids during human platelet activation. Study by fluorescent and freeze-fracture cytochemistry, Lab. Invest., 54, 136-142, 1986.
- Mora R., Eskenasy M., Hillebrand A., Simionescu M. Immunocytochemical localization of apoprotein B in the aorta during prelesional stages of hyperlipidemia in rabbit. Acta Biol. Hung., 37, 252-260, 1986.
- Muresan V. A hemagglutination test for hydrazide-derivatized cytochemical markers. Acta Histochem. 79, 193-198, 1986.
- Nistor A., Simionescu M. Uptake of low density lipoproteins by the hamster lung. Interaction with capillary endothelium. Am. Rev. Resp. Dis., 134, 1266-1272, 1986.
- Popov D., Alexandru D. Isolation and characterization of rabbit vascular and valvular glycosaminoglycans (GAGs). Rev. Roum. Biochim. 23, 135-143, 1986.
- Rus H.G., Niculescu F., Constantinescu E., Cristea A., Vlaicu R. Immunoelectron microscopic localization of the terminal C5b-9 complement complex in human atherosclerotic fibrous plaque. Atherosclerosis, 61, 35-42, 1986.
- Scurei C., Calb M., Simionescu N. Study on the endogenous lectins of the human platelet plasma membrane. Thromb. Res., 43, 15-31, 1986.
- Simionescu N., Vasile E., Lupu F., Popescu G., Simionescu M. Prelesional events in atherogenesis: accumulation of extracellular cholesterol rich liposomes in the arterial intima and cardiac valves of hyperlipidemic rabbits, Am. J. Pathol., 123, 85-101, 1986.
1985
- Ghinea N., Simionescu N. Anionized and cationized hemeundecapeptides as probes for cell surface charge and permeability studies: Differentiated labeling of endothelial plasmalemmal vesicles. J. Cell. Biol., 100, 606-612, 1985.
- Lupu F., Simionescu M. Organization of the intracellular junctions in the endothelium of the cardiac valves. J. Submicrosc. Cytol., 17, 119-132, 1985.
- Muresan V., M. Constantinescu. Distribution of sialoglycopconjugates on the luminal surface of the endothelial cell in the fenestrated capillaries of the pancreas. J. Histochem. Cytochem., 33, 474-476, 1985.
- Muresan V., M. Constantinescu. A mixed hemagglutination test for binding of glycosylated cytochemical markers. Anal. Biochem., 148, 503-509, 1985.
- Popov D. Proteoglicanii si glicozaminoglicanii membranari si rolul lor in interactiunile celulare. St. Cerc. Biochim., 28, 76-87, 1985.
- Simionescu M., Simionescu N., Santoro F., Palade G.E. Differential microdomains of the luminal plasmalemma of murine muscle capillaries: segmental variation in young and old animals. J. Cell Biol., 100, 1396-1407, 1985.
- Simionescu N., Simionescu M. Interaction of endogenous lipoproteins with capillary endothelium in spontaneously hyperlipoproteinemic rats. Microvasc. Res., 30, 314-332, 1985.
- Ciubotaru C., Alessandrescu D., Rusanescu T. Cresterea si maturarea placentara. Nota III. Consideratii privind fibronectina in dezvoltarea structurilor placentare; Obstetrica si Ginecologie, 33, 153-158, 1985.
1984
- Badea M., Jinga V.V., Hörer O. Experimental modulation on the plasmalemmal microfluidity. Studies on endothelial and aortic smooth muscle cells. Rev. Roum. Morphol. Embryol. Physiol.: Physiologie, 21, 39-44, 1984.
- Brown W.I., Constantinescu E., Farquhar M.G. Redistribution of mannose-6-phosphate receptors induced by tunicamycin and chloroquine. J. Cell Biol., 99, 320-326, 1984.
- Eskenasy M., Mora R., Simionescu N. In vitro study of low density lipoprotein-collagen interaction. Rev. Roum. Morphol. Embryol., 30, 147-152, 1984.
- Filip D. Mouse atrio-ventricular valve ultrastructure. Morphometrical correlations. Rev. Roum. Morphol. Embriol. Physiol.: Morphol. Embriol., 30, 163-173, 1984.
- Ghitescu L., Fixman A. Surface change distribution on the endothelial cell of liver sinusoids. J. Cell Biol., 99, 639-647, 1984.
- Heltianu C., Simionescu M., Simionescu N. Detection of histamine receptors at cellular level. Biochem. Pharmacol., 33, 343-446, 1984.
- Muresan V., Constantinescu M. Use of ferritin hydrazide for the detection sialoglycoconjugates. I. Methodological aspects. Rev. Roum. Biochim., 21, 189-197, 1984.
- Popov D. Study on proteins and sulfated glycoconjugates of the luminal surface of pulmonary vascular endothelium. Rev. Roum. Biochim., 21, 57-63, 1984.
- Simionescu N., Simionescu M., Palade G.E. Partial chemical characterization of the anionic sites in the basal lamina of fenestrated capillaries. Microvasc. Res., 28, 352-367, 1984.
- Haulica I., Neacsu C., Stratone A., Branisteanu D., Neamtu C., Rosca V., Petrescu Gh., Slatineanu C. Cardiovascular effects of the hog pineal E5 peptide in rats. Clin. Exp. - Theory and Practice, A6, 2091-2096, 1984.
1983
- Simionescu D., Simionescu M. Differentiated distribution of the cell surface charge on the alveolar-capillary unit. Characteristic paucity of anionic sites on the air-blood barrier. Microvasc. Res., 25, 85-101, 1983.
- Simionescu M. Cellular aspects of transcapillary exchanges. Physiol.Rev., 63,1563-1579, 1983.
- Simionescu N., Lupu F., Simionescu M. Rings of membrane sterols surround the opening of vesicles and fenestrae in capillary endothelium. J. Cell Biol., 97, 1592-1600, 1983.
- Vasile E., Nistor A., Simionescu M., Simionescu N. Visualization of the binding, endocytosis and transcytosis of low density lipoproteins in the arterial endothelium, in situ. J. Cell Biol., 96, 1677-1689, 1983.
1982
- Heltianu C., Simionescu M., Simionescu N. Histamine receptors of the microvascular endothelium revealed in situ with a histamine- ferritin conjugate: Characteristic high affinity binding sites in venules. J. Cell Biol., 93, 357-364, 1982.
- Muresan V., Sarras M.P.Jr., Jamieson J.D. Distribution of sialoglyconjugates on acinar cells of the mammalian pancreas. J. Histochem. Cytochem., 30, 947-955, 1982.
- Muresan V., Iwanij V., Zaid, Smith D.J., Jamieson J.D. Purification and use of limulin: A sialic acid - specific lectin. J. Histochem. Cytochem., 30, 938-946, 1982.
- Radu A., Dahl G., Loewenstein W.R. Hormonal regulation of cell junction permeability: upregulation by catecholamine and prostaglandin E1. J. Membr. Biol., 70, 239-251, 1982.
- Rosenfeld M.G., Kreibich G., Popov D., Kato A., Sabatini D. Biosynthesis of lysosomal hydrolases: Their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution. J. Cell Biol., 93, 135-143, 1982.
- Simionescu M., Simionescu N., Palade G.E. Preferential distribution of anionic sites on the basement membrane and the abluminal aspect of the endothelium, in fenestrated capillaries. J. Cell Biol., 95, 425-435, 1982.
- Simionescu M., Simionescu N., Palade G.E. Biochemically differentiated microdomains of the cell surface of capillary endothelium. Ann. N. Y. Acad. Sci., 401, 9-24, 1982.
- Simionescu N., Heltianu C., Antohe F., Simionescu M. Endothelial cell receptors for histamine. Ann. N. Y. Acad. Sci., 401, 132-149, 1982.
- Simionescu N., Simionescu M., Palade G.E. Differentiated microdomains on the luminal surface of capillary endothelium: distribution of lectin receptors. J. Cell Biol., 94, 406-413, 1982. Noteborn H.P.J.M., Ebels I., Pevet P.,
- Reinharz A.C., Neacsu C., Salemink C.A. Comparison of some peptidic and proteic ovine pineal fractions with E5 fraction. J. Neural Transmission, 55, 27-44, 1982.
1981
- Simionescu N., Simionescu M., Palade G.E. Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential distribution of anionic sites. J. Cell Biol., 90, 605-613, 1981.
- Simionescu M., Simionescu N., Palade G.E., Silbert J.E. Differentiated microdomains on the luminal surface of the capillary endothelium. II. Partial characterization of their anionic sites. J. Cell Biol., 90, 614-621, 1981.
- Palade G.E., Simionescu M., Simionescu N. Differentiated microdomains on the luminal surface of the capillary endothelium. Biorrheology, 17, 563- 568, 1981.
- Vaughan M.K., McGill J.R., Richardson B.A., Johnson L.Y., Pevet P., Neacsu C., Reiter R.J. Responsiveness of a prolactin-secreting clonal cell (288) or male rat hemipituitaries to incubation with arginine vasotocin, threonylseryllysine (TLS) or a partially purified peptide (E5) from bovine pineal glands. Neuroendocrinol. Lett. 3, 189-194, 1981.
- Pevet P., Neacsu C., Holder F.C., Reinharz A., Dogterom J., Buijs R.M., Guerne J.M., Vivien-Roels B. The vasotocin-like biological activity present in the bovine pineal is due to a compound different from vasotocin. J. Neural Transmission, 51, 295-302, 1981.
- Babes L., Draghici C., Teodorescu M., Tasca S.I. Studiu histochimic asupra distributiei prostaglandin-15-hidroxi-dehidrogenazei in tesuturile animale. St. Cerc. Biol., 1981.
1980
- Popov D. Sinteza proteinelor la eucariote. St. Cerc. Biochim. 23, 217-231, 1980.
1979
- Simionescu N. Enzymatic tracers in the study of vascular permeability. J. Histochem. Cytochem., 27, 1120-1130, 1979.
- Simionescu N., Palade G.E., Simionescu M. Structural aspects of the permeability in the microvascular endothelium. Acta Physiol. Scand. Suppl., 463, 11-32, 1979.
- Noteborn H.P.J.M., Ebels I., Pevet P., Reinharz A.C., Neacsu C., Salemink C.A. Comparison of some peptidic and proteic ovine pineal fractions with E5 fraction. J. Neural Transmission, 55, 27-44, 1982.