About Us

RESEARCH STRATEGY

Integration of the biomedical research into the modern precision medicine.

Using smart approaches based on mass spectrometry proteomics and wet laboratory methods we aim to develop translational personalized biomedicine. Uncover the inter-relation of basic structural and functional proteomics with clinical patients’ profile will lead to early diagnostic, prevention and adequate personalized therapies.

Major research interests of the department:

• The application of mass spectrometry-based proteomics for biomarker research in chronic non-communicable diseases (atherosclerosis, type 1 and 2 diabetes, gestational diabetes, diabetic foot syndrome, cancer);
• The investigation of DAMPs as potential predictors and therapeutic targets in inflammatory pathologies;
• Identification of markers and mechanisms involved in cardiac recovery post-myocardial infarction;
• Uncovering mechanisms of early atherosclerosis and/or plaque instability in coronary artery disease;
• Membrane microdomains (lipid rafts, plasmalemmal vesicles, caveolae): structural and functional characterization;
• Transport of macromolecules in vascular cells: cell receptors, transcytosis, endocytosis.